Sampathkumar Krishnaswamy, Sooraj Yesudas S, Mahaldar Amol R, Ramakrishnan Muthiah, Rajappannair Ajeshkumar, Nalumakkal Seethalekshmy V, Erode Elango
Department of Nephrology, Meenakshi Mission Hospital and Research Centre, Lake Area, Melur Road, Madurai, Tamil Nadu, India.
Saudi J Kidney Dis Transpl. 2009 Sep;20(5):842-5.
Granulomatous interstitial nephritis (GIN) is an uncommon form of acute interstitial nephritis. We report a young male who presented to us with a rapidly progressing renal failure and massive proteinuria. A renal biopsy revealed GIN, and we were able to demonstrate the presence of tuberculous DNA in the biopsy specimen. The patient was started on anti-tuberculous therapy and steroids besides 11 sessions of hemodialysis. He recovered and is currently doing well. This case highlights an uncommon manifestation of renal tuberculosis, namely massive proteinuria, acute renal failure, and granulomatous interstitial lesions.
肉芽肿性间质性肾炎（GIN）是急性间质性肾炎的一种罕见形式。我们报告了一名年轻男性，他因快速进展的肾衰竭和大量蛋白尿前来就诊。肾活检显示为GIN，并且我们能够在活检标本中证实结核DNA的存在。除了进行11次血液透析外，该患者开始接受抗结核治疗和类固醇治疗。他康复了，目前情况良好。该病例突出了肾结核的一种罕见表现，即大量蛋白尿、急性肾衰竭和肉芽肿性间质病变。
