Kaul Anupma, K Sharma Raj, Krishnasamy Jaisuresh, Ruhela Vivek, Kumari Niraj
Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttarpradesh, India.
Department of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttarpradesh, India.
NDT Plus. 2011 Dec;4(6):383-5. doi: 10.1093/ndtplus/sfr067. Epub 2011 Jul 18.
Granulomatous interstitial nephritis (GIN) is a rare manifestation of renal tuberculosis (TB). We report a case of rapidly progressive renal failure (RPRF), granulomatous inflammation of cervical lymph node and GIN as presenting manifestations of TB. Aspiration cytology of cervical lymph node showed granulomatous necrotizing inflammation with acid-fast bacilli (AFB). The renal biopsy and urine specimen did not show AFB. Urine polymerase chain reaction (PCR) for Mycobacterium tuberculosis was positive. We observe that GIN due to TB can present as RPRF and emphasize the value of PCR-based techniques in making a correct diagnosis.
肉芽肿性间质性肾炎（GIN）是肾结核（TB）的一种罕见表现。我们报告一例以快速进展性肾衰竭（RPRF）、颈部淋巴结肉芽肿性炎症和GIN为表现的肾结核病例。颈部淋巴结穿刺细胞学检查显示肉芽肿性坏死性炎症伴抗酸杆菌（AFB）。肾活检和尿液标本未发现AFB。结核分枝杆菌尿液聚合酶链反应（PCR）呈阳性。我们观察到，结核引起的GIN可表现为RPRF，并强调基于PCR技术在正确诊断中的价值。
