Dallimore Jon, Rowbotham Emma C
Department of Emergency Medicine, Bristol Royal Infirmary, Bristol, United Kingdom.
Wilderness Environ Med. 2009 Fall;20(3):221-4. doi: 10.1580/07-WEME-OR-119R3.1.
To measure the incidence of acute mountain sickness (AMS) in adolescents travelling to moderately high altitudes.
The study was carried out on a cohort of 63 adolescents with an average age of 15.9 years during an 8-day trip to Morocco, travelling to altitudes between 3106 m and 4167 m. The incidence of AMS was calculated using the Lake Louise questionnaire, which was completed twice daily by each participant. An episode of AMS was defined as being a score of 3 or more on the Lake Louise questionnaire in the presence of a headache. Difference in incidence between boys and girls was analyzed using 2-tailed Mann-Whitney U testing.
The daily incidence of AMS among 52 participants with complete data was found to be between 3.8% and 42.3% and increased with increasing altitude. Girls had a statistically significant higher incidence of AMS (80%) compared with boys (55%) (P < .01).
Acute mountain sickness may occur more commonly in female adolescents than in male adolescents. Overall, however, it appears that the incidence of AMS in adolescents is similar to that found in adults in previous studies.
测量前往中度高海拔地区旅行的青少年急性高原病（AMS）的发病率。
该研究对63名平均年龄为15.9岁的青少年进行，他们在前往摩洛哥的8天旅行中，前往海拔3106米至4167米的地区。使用路易斯湖问卷计算AMS的发病率，每位参与者每天填写两次该问卷。AMS发作被定义为在头痛情况下路易斯湖问卷得分3分或更高。使用双尾曼-惠特尼U检验分析男孩和女孩发病率的差异。
在52名有完整数据的参与者中，AMS的每日发病率在3.8%至42.3%之间，并随海拔升高而增加。女孩的AMS发病率（80%）在统计学上显著高于男孩（55%）（P < .01）。
女性青少年急性高原病的发生可能比男性青少年更常见。然而，总体而言，青少年AMS的发病率似乎与先前研究中成年人的发病率相似。
