Schneider M A, Brotherton P L, Hailes J
Med J Aust. 1977 Jul 30;2(5):162-3. doi: 10.5694/j.1326-5377.1977.tb99116.x.
A study of the effects of conjugated oestrogens (Premarin) upon the depression scores of depressed and non-depressed menopausal women was carried out. Depression levels were obtained for both groups before and after four weeks of hormone replacement therapy. The Beck Depression Inventory (BDI) was used to assess depression levels, while a semistructured interview provided information related to the physiological, psychological and sociocultural stresses affecting individual women. Depression scores of the depressed group did not improve within the given treatment period, in contrast with improved scores for the non-depressed subjects who reported increased feelings of well-being following hormone replacement therapy.
开展了一项关于结合雌激素(倍美力)对抑郁和非抑郁绝经后女性抑郁评分影响的研究。在激素替代治疗四周前后,分别获取了两组的抑郁水平。使用贝克抑郁量表(BDI)评估抑郁水平,同时通过半结构化访谈提供与影响个体女性的生理、心理和社会文化压力相关的信息。与非抑郁受试者的评分改善形成对比的是,抑郁组的抑郁评分在给定治疗期内没有改善,非抑郁受试者报告称激素替代治疗后幸福感增强。