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撒哈拉以南非洲农村地区先天性心脏病的发生率及模式

Occurrence and pattern of congenital heart diseases in a rural area of sub-Saharan Africa.

作者信息

Tantchou Tchoumi J C, Butera G, Giamberti A, Ambassa J C, Sadeu J C

机构信息

Cardiac Centre, St Elizabeth Catholic General Hospital, Shisong, Kumbo, Cameroon.

出版信息

Cardiovasc J Afr. 2011 Mar-Apr;22(2):63-6. doi: 10.5830/cvja-2010-046.

Abstract

UNLABELLED

The extent of congenital heart disease in Cameroon remains largely unknown. The aim of this study was to determine the occurrence and pattern of congenital heart diseases in the Cardiac Centre of St Elizabeth Catholic General Hospital, situated in a rural area of Cameroon.

METHODS

Between November 2002 and November 2008, a population of 2 123 patients with suspected cardiac pathologies were consulted at St Elizabeth Catholic General Hospital referral cardiac centre. Of these patients, 292 subjects were recruited for the study, based on detection of (1) precordial murmurs and/or cardiomegaly on chest X-ray examination, or (2) congenital heart diseases on transthoracic Doppler echocardiography examination.

RESULTS

Congenital heart diseases and inorganic murmurs were found in 95.5 and 4.5% of the patients, respectively. Congenital heart diseases included tetralogy of Fallot (26.1%), isolated ventricular septal defect (38.8%), atrioventricular cushion defect (7.3%), isolated atrial septal defect (2.8%), arterial duct cases (12.4%), common arterial trunk (1.3%), isolated stenosis of the pulmonary artery (2.6%), coarctation of the aorta (1.1%), congenital mitral valve regurgitation (1.2%), atresia of the triscupid valve (1.6%), double-outlet right ventricle (2.1%), anomalous pulmonary venous return (1.5%) and left isomerism (1.2%).

CONCLUSION

Our data show that there is a high occurrence of congenital heart disease in this hospital in a rural zone of sub-Saharan Africa and that isolated ventricular septal defect is the predominant pathology. Post-surgical follow up remains very challenging as many parents cannot afford their children's medical treatment or are generally not well educated.

摘要

未标注

喀麦隆先天性心脏病的实际情况在很大程度上仍不为人知。本研究旨在确定位于喀麦隆农村地区的圣伊丽莎白天主教综合医院心脏中心先天性心脏病的发病情况及模式。

方法

2002年11月至2008年11月期间,圣伊丽莎白天主教综合医院心脏科转诊中心接待了2123名疑似心脏疾病患者。在这些患者中,基于以下情况招募了292名受试者进行研究:(1)胸部X光检查发现心前区杂音和/或心脏扩大,或(2)经胸多普勒超声心动图检查发现先天性心脏病。

结果

分别在95.5%和4.5%的患者中发现先天性心脏病和非器质性杂音。先天性心脏病包括法洛四联症(26.1%)、单纯室间隔缺损(38.8%)、房室间隔缺损(7.3%)、单纯房间隔缺损(2.8%)、动脉导管未闭病例(12.4%)、共同动脉干(1.3%)、单纯肺动脉狭窄(2.6%)、主动脉缩窄(1.1%)、先天性二尖瓣反流(1.2%)、三尖瓣闭锁(1.6%)、右心室双出口(2.1%)、肺静脉异位引流(1.5%)和左心异构(1.2%)。

结论

我们的数据表明,在撒哈拉以南非洲农村地区的这家医院,先天性心脏病的发病率很高,且单纯室间隔缺损是主要病变。由于许多家长负担不起孩子的医疗费用或普遍文化程度不高,术后随访仍然极具挑战性。

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