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用于鼻气流数值模拟的入口边界轮廓规定。

Inflow boundary profile prescription for numerical simulation of nasal airflow.

机构信息

Department of Aeronautics, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.

出版信息

J R Soc Interface. 2010 Mar 6;7(44):515-27. doi: 10.1098/rsif.2009.0306. Epub 2009 Sep 9.

Abstract

Knowledge of how air flows through the nasal passages relies heavily on model studies, as the complexity and relative inaccessibility of the anatomy prevents detailed in vivo measurement. Almost all models to date fail to incorporate the geometry of the external nose, instead employing a truncated inflow. Typically, flow is specified to enter the model domain either directly at the nares (nostrils), or via an artificial pipe inflow tract attached to the nares. This study investigates the effect of the inflow geometry on flow predictions during steady nasal inspiration. Models that fully replicate the internal and external nasal airways of two anatomically distinct subjects are used as a reference to compare the effects of common inflow treatments on physiologically relevant quantities including regional wall shear stress and particle residence time distributions. Inflow geometry truncation is found to affect flow predictions significantly, though slightly less so for the subject displaying more pronounced passage area contraction up to the internal nasal valve. For both subject geometries, a tapered pipe inflow provides a better approximation to the natural inflow than a blunt velocity profile applied to the nares. Computational modelling issues are also briefly outlined, by comparing quantities predicted using different surface tessellations, and by evaluation of domain-splitting techniques.

摘要

关于空气如何流经鼻腔的知识在很大程度上依赖于模型研究,因为鼻腔的解剖结构复杂且相对难以进入,这使得对其进行详细的体内测量变得困难。迄今为止,几乎所有的模型都未能纳入外鼻的几何形状,而是采用了截断的入口。通常,流动被指定为直接从鼻腔(鼻孔)进入模型域,或者通过附着在鼻腔上的人工管道入口进入模型域。本研究考察了入口几何形状对稳态鼻吸气期间流动预测的影响。使用完全复制两个解剖上不同的受试者的内部和外部鼻气道的模型作为参考,以比较常见的入口处理方法对包括局部壁面剪切应力和颗粒停留时间分布在内的生理相关量的影响。发现入口几何形状的截断对流动预测有显著影响,但对于显示出更明显的通道区域收缩直到内部鼻阀的受试者的影响稍小。对于这两种受试者的几何形状,锥形管入口比施加在鼻孔上的钝速剖面更能近似自然入口。通过比较使用不同表面剖分的预测量,并通过评估域分割技术,简要概述了计算建模问题。

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本文引用的文献

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Mechanics of airflow in the human nasal airways.人类鼻腔气道中的气流机制。
Respir Physiol Neurobiol. 2008 Nov 30;163(1-3):100-10. doi: 10.1016/j.resp.2008.07.027. Epub 2008 Aug 14.
2
Experimental investigation of nasal airflow.鼻腔气流的实验研究
Proc Inst Mech Eng H. 2008 May;222(4):439-53. doi: 10.1243/09544119JEIM330.
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Nasal architecture: form and flow.鼻腔结构:形态与气流
Philos Trans A Math Phys Eng Sci. 2008 Sep 28;366(1879):3225-46. doi: 10.1098/rsta.2008.0083.
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Air-conditioning in the human nasal cavity.人类鼻腔中的空气调节
Respir Physiol Neurobiol. 2008 Nov 30;163(1-3):121-7. doi: 10.1016/j.resp.2008.05.002. Epub 2008 May 9.
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Atrophic rhinitis: a CFD study of air conditioning in the nasal cavity.萎缩性鼻炎:鼻腔内空调环境的计算流体动力学研究
J Appl Physiol (1985). 2007 Sep;103(3):1082-92. doi: 10.1152/japplphysiol.01118.2006. Epub 2007 Jun 14.
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Physical stresses at the air-wall interface of the human nasal cavity during breathing.
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