Division of General Internal Medicine, Kyushu Dental College, Manazuru 2-6-1, Kokurakita-ku, Kitakyushu City, 803-8580, Japan.
J Oral Rehabil. 2009 Nov;36(11):808-13. doi: 10.1111/j.1365-2842.2009.01998.x. Epub 2009 Sep 10.
Although the number of sound or decayed teeth has been reported to be associated with cognitive function in elderly populations with dementia, little is known about this association in elderly populations without dementia. We evaluated this relationship, with adjustment for confounding factors, in Japanese populations of 60-year-old (n = 270; 120 males and 150 females) and 65-year-old (n = 123; 57 males and 66 females) individuals residing in Fukuoka Prefecture of Japan. Dental examinations were performed in all subjects, along with the Mini-mental state examination (MMSE) for assessing cognitive function. Among the total of 393 subjects, the mean MMSE score was 27.9 +/- 1.9, and 391 subjects scored 24 or higher. The mean numbers of sound and decayed teeth were 12.0 +/- 6.3 and 0.5 +/- 1.2, respectively. Associations were found between the numbers of sound and decayed teeth and MMSE in total subjects and males, but not in females, by multiple regression analysis adjusted for gender, age, level of education, marital status, smoking, alcohol drinking, working status, systolic blood pressure and blood glucose. An association was also found between MMSE and the number of sound teeth in a logistic regression analysis. In conclusion, associations were found between normal-range cognitive function and the numbers of sound and decayed teeth, after adjustment for various confounding factors, in an elderly Japanese population.
虽然有报道称,在患有痴呆症的老年人群中,牙齿的数量与认知功能有关,但在没有痴呆症的老年人群中,这种关联知之甚少。我们评估了这种相关性,在日本福冈县的 60 岁(n=270;男性 120 人,女性 150 人)和 65 岁(n=123;男性 57 人,女性 66 人)的人群中,对这些因素进行了调整。所有受试者都接受了牙齿检查,并进行了 Mini-mental 状态检查(MMSE)以评估认知功能。在总共 393 名受试者中,平均 MMSE 得分为 27.9 +/- 1.9,391 名受试者得分 24 或更高。健康牙齿和龋齿的平均数量分别为 12.0 +/- 6.3 和 0.5 +/- 1.2。多元回归分析发现,在总人群和男性中,健康牙齿和龋齿的数量与 MMSE 呈正相关,但在女性中无相关性。多因素回归分析发现,在调整了性别、年龄、教育水平、婚姻状况、吸烟、饮酒、工作状况、收缩压和血糖等混杂因素后,MMSE 与健康牙齿数量之间也存在相关性。总之,在调整了各种混杂因素后,在日本老年人群中,正常认知功能与健康牙齿和龋齿的数量之间存在相关性。