Department of Endocrinology, Diabetology and Metabolic Disease, Avicenne Hospital, Paris XIII University (CRNH), 93009 Bobigny cedex, France.
Ann Endocrinol (Paris). 2009 Dec;70(6):468-72. doi: 10.1016/j.ando.2009.06.033. Epub 2009 Sep 10.
We report a case of a medullary thyroid carcinoma discovered by F-18 fluorodeoxyglucose-positron emission tomography (F-18 FDG PET).
A 73-year-old man with a history of surgical removal of sigmoid colon cancer underwent F-18 FDG PET to search for distant metastases and / or local recurrence because of elevated CEA level and new episode of occlusion. F-18 FDG PET images showed increased focal FDG uptake in the right lobe of the thyroid. Thyroid ultrasound showed one thyroid nodule in each lobe.
The fine needle aspiration result was suspicious and calcitonin level was elevated. The subject underwent thyroidectomy without lymph node dissection. The pathology showed a 14 mm medullary thyroid carcinoma. There was no germline mutation of RET.
F-18 FDG PET can detect primitive or secondary malignant thyroid tumors. Thus, thyroid incidentaloma revealed by 18 FDG PET uptake always necessitates careful evaluation.
我们报告了一例通过 F-18 氟脱氧葡萄糖正电子发射断层扫描（F-18 FDG PET）发现的甲状腺髓样癌病例。
一名 73 岁男性，因 CEA 水平升高和新出现的阻塞而接受 F-18 FDG PET 以寻找远处转移和/或局部复发，该患者曾行乙状结肠癌切除术。F-18 FDG PET 图像显示右叶甲状腺有局灶性 FDG 摄取增加。甲状腺超声显示每个叶均有一个甲状腺结节。
细针抽吸结果可疑，降钙素水平升高。患者行甲状腺切除术，未行淋巴结清扫术。病理显示 14 毫米甲状腺髓样癌。无 RET 种系突变。
F-18 FDG PET 可检测原始或继发性恶性甲状腺肿瘤。因此，通过 18 FDG PET 摄取发现的甲状腺意外瘤总是需要仔细评估。
