Emergency Department, Piacenza Hospital, Italy.
Thromb Res. 2009 Nov;124(5):e32-40. doi: 10.1016/j.thromres.2009.08.006. Epub 2009 Sep 9.
The treatment of venous thromboembolism (VTE) in cancer patients remains controversial.
The Italian Society for Thrombosis and Haemostasis (SISET) commissioned a project to develop clinical practice guidelines for the therapy of VTE in patients with malignancies.
Key questions about the treatment of VTE in patients with malignancies were formulated by a multidisciplinary working group consisting of experts in clinical medicine and research. After a systematic review and discussion of the literature, recommendations were formulated and graded according to the supporting evidence. For those questions for which the literature search did not yield any definitive answer (absence of evidence evidence of low quality, and contradictory evidence), a formal consensus method was used to issue clinical recommendations.
The results of the available literature on VTE treatment in cancer patients were reviewed and clinical recommendations were drafted.
We describe the results of a systematic literature review and an explicit approach to consensus techniques which resulted in recommendations for the key therapeutic issues in cancer patients with VTE.
癌症患者静脉血栓栓塞症（VTE）的治疗仍然存在争议。
意大利血栓与止血学会（SISET）委托开展了一个项目，旨在为恶性肿瘤患者 VTE 的治疗制定临床实践指南。
由临床医学和研究领域的专家组成的多学科工作组提出了关于恶性肿瘤患者 VTE 治疗的关键问题。在对文献进行系统回顾和讨论后，根据证据支持程度制定了建议，并进行了分级。对于那些文献检索没有得出明确答案的问题（缺乏证据、证据质量低和相互矛盾的证据），采用正式的共识方法发布临床建议。
对癌症患者 VTE 治疗的现有文献进行了回顾，并起草了临床建议。
我们描述了系统文献综述和明确的共识技术方法的结果，这些结果为 VTE 癌症患者的关键治疗问题提供了建议。
