Department of Radiology, Institut Claudius Regaud, 20-24 rue du Pont Saint Pierre, 31052 Toulouse, France.
Eur J Radiol. 2009 Oct;72(1):50-3. doi: 10.1016/j.ejrad.2009.05.027. Epub 2009 Sep 9.
The role of systematic magnetic resonance imaging (MRI) after resection of soft tissue sarcomas (STS) of the limb is opened to debate. The aim of our study was to retrospectively evaluate the effectiveness of a systematic MRI examination performed in 124 adult patients treated between 1996 and 2006 for a non-metastatic limb STS at our centre: 86 patients (70%) had clear resection margins (R0) and 111 patients (90%) received an adjuvant radiotherapy. Among the 11 local recurrences (9%) which were observed, MRI was able to detect only 2 asymptomatic local recurrences, one with and one without synchronous metastasis. Both had microscopically involved margins (R1). In contrast, MRI showed 11 false positive cases. As the predictive positive value of MRI was 42%, clinical follow-up seems to be more effective. As observed in our study, systematic MRI examination is not relevant for the follow-up of all limb soft tissue sarcomas. A prospective study could be promoted to evaluate the role of MRI in patients at high risk of local recurrence.
肢体软组织肉瘤（STS）切除术后进行系统磁共振成像（MRI）的作用存在争议。我们的研究旨在回顾性评估我们中心 1996 年至 2006 年间治疗的 124 例非转移性肢体 STS 成人患者进行系统 MRI 检查的效果：86 例患者（70%）有明确的切除边缘（R0），111 例患者（90%）接受了辅助放疗。在观察到的 11 例局部复发（9%）中，MRI 仅能检测到 2 例无症状的局部复发，其中 1 例伴有同步转移，1 例无同步转移。两者均有显微镜下累及的边缘（R1）。相比之下，MRI 显示出 11 例假阳性病例。由于 MRI 的预测阳性值为 42%，临床随访似乎更有效。正如我们的研究观察到的，系统 MRI 检查对于所有肢体软组织肉瘤的随访并不相关。可以进行前瞻性研究来评估 MRI 在局部复发高风险患者中的作用。
