MMWR Morb Mortal Wkly Rep. 2009 Sep 11;58(35):975-8.
In the future, when wild poliovirus (WPV) transmission is interrupted worldwide, facilities holding WPV materials will represent the only remaining repository of the virus. Maintaining the number of such facilities at a minimum and at an appropriate biosafety standard (laboratory containment) reduces the risk for a facility-associated reintroduction of WPV. In May 1999, the World Health Assembly (WHA) urged all member states to begin the process leading to laboratory containment of WPV. The World Health Organization (WHO) global action plan for laboratory containment of WPV issued in 1999 indicated a staged approach that begins with a national survey of all biomedical facilities (Phase I); the purpose of the survey is to alert institutions and facilities to the need for containment, encourage reduction of WPV materials, and develop a national inventory of facilities holding such materials. The survey and inventory provide a facility database for use in all subsequent steps toward global poliovirus containment. In May 2008, WHA urged all WHO member states to complete Phase I activities outlined in the WHO Global Action Plan for Laboratory Containment of Wild Polioviruses. In the WHO Western Pacific Region (WPR), Phase I surveys of 77,260 laboratories in the 37 countries and areas of WPR were conducted during 1999--2008. A total of 45 laboratories were identified as holding WPV materials in 2008. This report describes completion of Phase I containment activities by WPR countries, and updates a previous report on Phase I completion in the European Region and global progress.
未来,当全球范围内野生脊髓灰质炎病毒(WPV)传播被阻断后,持有WPV材料的设施将成为该病毒仅存的储存库。将此类设施的数量维持在最低水平并符合适当的生物安全标准(实验室防护水平),可降低因设施关联导致WPV重新引入的风险。1999年5月,世界卫生大会(WHA)敦促所有成员国启动实现WPV实验室防护的进程。世界卫生组织(WHO)1999年发布的WPV实验室防护全球行动计划指出了一种分阶段方法,该方法始于对所有生物医学设施进行全国性调查(第一阶段);调查目的是使各机构和设施认识到防护的必要性,鼓励减少WPV材料,并编制持有此类材料的设施的国家清单。该调查和清单提供了一个设施数据库以供后续所有全球脊髓灰质炎病毒防护步骤使用。2008年5月,WHA敦促所有WHO成员国完成《WHO野生脊髓灰质炎病毒实验室防护全球行动计划》中概述的第一阶段活动。在WHO西太平洋区域(WPR),1999年至2008年期间对WPR 地区37个国家和地区的77,260个实验室进行了第一阶段调查。2008年共确定45个实验室持有WPV材料。本报告描述了WPR国家第一阶段防护活动的完成情况,并更新了之前关于欧洲区域第一阶段完成情况和全球进展的报告。