掺钪沸石作为新型多相催化剂： Mukaiyama 羟醛缩合反应。

Sc(III)-doped zeolites as new heterogeneous catalysts: mukaiyama aldol reaction.

机构信息

Laboratoire de Physicochimie des Hydrocarbures, Institut de Chimie de Strasbourg, 4 rue Blaise Pascal, 67000 Strasbourg, France.

出版信息

Chemistry. 2009 Oct 26;15(42):11229-34. doi: 10.1002/chem.200901647.

DOI:10.1002/chem.200901647

PMID:19746487

Abstract

Sc(III)-doped solids based on zeolite materials have been investigated for the first time as catalysts in organic synthesis. Sc(III)-USY zeolite proved to be a novel and very efficient heterogeneous catalyst for the Mukaiyama aldol reaction. This easy-to-prepare catalyst exhibited wide scope and compatibility with functional groups and is very simple to use, easy to remove (by simple filtration), and is recyclable (up to three times without loss of activity).

摘要

首次研究了基于沸石材料的 Sc(III)-掺杂固体作为有机合成中的催化剂。Sc(III)-USY 沸石被证明是 Mukaiyama 缩醛反应的一种新型、非常高效的多相催化剂。这种易于制备的催化剂具有广泛的适用性和官能团兼容性，使用非常简单，易于去除（通过简单过滤），并且可回收（重复使用三次而不损失活性）。