Department of Conservative Dentistry, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8504, Japan.
Dent Mater. 2010 Jan;26(1):29-34. doi: 10.1016/j.dental.2009.08.011.
Ammonium hexafluorosilicate [SiF: (NH(4))(2)SiF(6)] was prepared in order to overcome the tooth discoloration caused by diamine silver fluoride [AgF: (NH(3))(2)AgF] application. We employed a single concentration of SiF solution in our previous study; therefore, it is still unclear how the concentration of SiF solution affects the occlusion of dentin tubules and composition of the precipitate.
The aim of this study was to evaluate the effects of changing the concentration of SiF on its clinical use as a dentin hypersensitivity treatment.
To simulate dentin tubules subject to dentin hypersensitivity, dentin disks were treated with EDTA for 2 min. Then, the disks were treated with several concentrations of SiF solution (from 100 to 19,400 ppm) for 3 min. The occlusion of dentin tubules was evaluated using scanning electron microscopy (SEM), and the composition of the precipitate formed in the tubules after SiF treatment was assessed using energy dispersive X-ray analysis (EDXA).
SEM photographs demonstrated that dentin tubules after treatment with SiF were occluded homogeneously and fully regardless of the concentration of SiF solution. The Ca/P molar ratio of the precipitate formed in dentin tubules after SiF treatment was increased with the concentration of SiF solution.
It was concluded that the capacity to occlude dentin tubules was the same regardless of the concentration of SiF solution. However, the composition of the precipitate formed in the tubules was dependent on the concentration of SiF solution.
六氟硅酸铵[SiF：（NH（4））（2）SiF（6）]是为了克服因二胺氟化银[AgF：（NH（3））（2）AgF]应用而引起的牙齿变色而制备的。在我们之前的研究中，我们使用了单一浓度的 SiF 溶液；因此，SiF 溶液的浓度如何影响牙本质小管的闭塞和沉淀物的组成仍不清楚。
本研究旨在评估改变 SiF 浓度对其作为牙本质敏感症治疗的临床应用的影响。
为了模拟牙本质小管受到牙本质敏感症的影响，用 EDTA 处理牙本质圆盘 2 分钟。然后，将圆盘用几种浓度的 SiF 溶液（从 100 到 19400 ppm）处理 3 分钟。使用扫描电子显微镜（SEM）评估牙本质小管的闭塞情况，并使用能量色散 X 射线分析（EDXA）评估 SiF 处理后在小管中形成的沉淀物的组成。
SEM 照片表明，用 SiF 处理后的牙本质小管均匀且完全闭塞，而与 SiF 溶液的浓度无关。SiF 处理后在牙本质小管中形成的沉淀物的 Ca/P 摩尔比随着 SiF 溶液浓度的增加而增加。
结论是，闭塞牙本质小管的能力与 SiF 溶液的浓度无关。然而，在小管中形成的沉淀物的组成取决于 SiF 溶液的浓度。
