Bershteyn Anna, Chaparro José, Yau Richard, Kim Mikyung, Reinherz Ellis, Ferreira-Moita Luis, Irvine Darrell J
Department of Materials Science and Engineering, and Biological Engineering, Massachusetts Institute of Technology Room 8-425, 77, Massachusetts Avenue, Cambridge, MA 02139. ;, Tel: +1 617 452 4174.
Soft Matter. 2008;4(9):1787-1791. doi: 10.1039/b804933e.
Phospholipid-enveloped biodegradable polymer microparticles and nanoparticles synthesized by an emulsion/solvent evaporation process were characterized by confocal and cryoelectron microscopies to show that the lipid envelope exhibits two-dimensional fluidity and can be configured into 'shell', 'onion', or 'flower' nanostructures, depending on the quantity and composition of lipids employed in the synthesis.
通过乳液/溶剂蒸发法合成的磷脂包被的可生物降解聚合物微粒和纳米颗粒，经共聚焦显微镜和冷冻电子显微镜表征，结果表明脂质包膜具有二维流动性，并且根据合成中所用脂质的数量和组成，可以构建成“壳”、“洋葱”或“花”状纳米结构。
