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地中海内脏利什曼病患者的抗原血症。

Antigenemia in patients with mediterranean visceral leishmaniasis.

机构信息

Bâtiment Universitaire Archimed, INSERM U895, C3M, Equipe 6, 151 Route St Antoine de Ginestière, BP 2 3194, 06204 Nice Cedex 3, France.

出版信息

J Clin Microbiol. 2009 Nov;47(11):3760-2. doi: 10.1128/JCM.00649-09. Epub 2009 Sep 16.

DOI:10.1128/JCM.00649-09
PMID:19759231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2772584/
Abstract

Antigenemia in patients with Mediterranean visceral leishmaniasis (MVL) due to Leishmania infantum was retrospectively assessed by sandwich enzyme-linked immunosorbent assay (ELISA). Circulating Leishmania antigens, partially in free form, were in evidence in 53% of serum samples from immunocompetent individuals with MVL. Following successful therapy, antigenemia decline as measured by ELISA was more pronounced than antibody decrease.

摘要

采用夹心酶联免疫吸附试验（ELISA）法对因感染婴儿利什曼原虫而导致的地中海内脏利什曼病（MVL）患者的抗原血症进行了回顾性评估。在免疫功能正常的 MVL 患者的血清样本中，有 53%检测到了部分以游离形式存在的循环利什曼原虫抗原。经成功治疗后，ELISA 检测到的抗原血症下降程度比抗体下降更为显著。

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本文引用的文献

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