[II型牙本质发育不全患者的家系分析与口腔修复治疗]
[Pedigree analysis and prosthodontic treatment of patients with dentinogenesis imperfecta type II].
作者信息
Gan Hong, Zhang Xiu-yin, Xu Xiao-cen
机构信息
Department of Prosthodontics, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai 200011, China.
出版信息
Shanghai Kou Qiang Yi Xue. 2009 Aug;18(4):337-41.
PURPOSE
To study the heritable character and explore the prosthodontic treatment of opalescent dentin, also known as dentinogenesis imperfecta type II(DGI-II).
METHODS
Pedigree analysis was performed in the family members of patients with DGI-II found in Shanghai. The proband was treated with ceramometal restorations and investigated the treatment status of the DGI-II affected individuals in the family.
RESULTS
Five sequential generations with DGI-II were found in this family. The prevalence of later generation was approximately 50%. The rate of prosthodontic treatment was 90% nearly, including ceramometal restorations in the most of the patients and removable partial dentures in the others. The esthetic and mastication functions of the patients were good after treatment.
CONCLUSIONS
DGI-II showed a autosomal dominant pattern of inheritance. Ceramaometal restorations can prevent the affected teeth from abrasive and fracture, and also can help rehabilitate the esthetic and mastication functions of the teeth.
目的
研究遗传性乳光牙本质（又称Ⅱ型牙本质发育不全，DGI-II）的遗传特征并探索其修复治疗方法。
方法
对在上海发现的DGI-II患者的家庭成员进行家系分析。先证者接受烤瓷熔附金属全冠修复治疗，并调查该家族中DGI-II患者的治疗情况。
结果
该家族发现连续五代患有DGI-II。后代患病率约为50%。修复治疗率近90%，大多数患者采用烤瓷熔附金属全冠修复，其他患者采用可摘局部义齿修复。治疗后患者的美观和咀嚼功能良好。
结论
DGI-II呈常染色体显性遗传模式。烤瓷熔附金属全冠修复可防止患牙磨损和折断，还能帮助恢复牙齿的美观和咀嚼功能。
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