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PoreLogo:一种用于分析、可视化和比较跨膜蛋白通道的新工具。

PoreLogo: a new tool to analyse, visualize and compare channels in transmembrane proteins.

机构信息

Department of Applied Sciences, University of Parthenope of Naples, Centro Direzionale Isola C4 80143, Naples, Italy.

出版信息

Bioinformatics. 2009 Dec 1;25(23):3183-4. doi: 10.1093/bioinformatics/btp545. Epub 2009 Sep 17.

Abstract

UNLABELLED

The increasing number of available atomic 3D structures of transmembrane channel proteins represents a valuable resource for better understanding their structure-function relationships and to eventually predict their selectivity. Herein, we present PoreLogo, an automatic tool for analysing, visualizing and comparing the amino acid composition of transmembrane channels and its conservation across the corresponding protein family.

AVAILABILITY

PoreLogo is accessible as a public web server at http://www.ebi.ac.uk/thornton-srv/software/PoreLogo/.

摘要

未加标签

越来越多可用的跨膜通道蛋白的原子 3D 结构代表了更好地理解它们的结构-功能关系并最终预测其选择性的宝贵资源。在此,我们介绍了 PoreLogo,这是一种用于分析、可视化和比较跨膜通道的氨基酸组成及其在相应蛋白质家族中的保守性的自动工具。

可用性

PoreLogo 可作为公共网络服务器在 http://www.ebi.ac.uk/thornton-srv/software/PoreLogo/ 上获得。

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