Department of Radiology and Magnetic Resonance Tomography, Christian Doppler Clinic, Paracelsus Medical University, Salzburg, Austria.
Eur Radiol. 2010 Apr;20(4):870-6. doi: 10.1007/s00330-009-1604-2. Epub 2009 Sep 16.
We compared experimental rabbit carotid bifurcation aneurysms embolised with platinum coils or hydrogel filaments by using digital subtraction angiography (DSA) and computed tomography angiography (CTA).
Embolisation was performed using platinum coils (n = 2), hydrogel filaments loaded with iodine (n = 3) and hydrogel filaments loaded with barium sulphate (n = 3). In one case, a stent was deployed in the parent vessel to determine the effect of hydrogel filaments on stent visualisation. DSA evaluations occurred immediately post-treatment. CTA evaluations occurred at 0-13 weeks post-treatment. The DSA and CTA images were evaluated for the lack of artefacts and the visibilities of the embolic mass, individual coils and residual flow in the aneurysm sac and neck.
The DSA results were largely concordant among the three groups. The embolic masses were readily evident with some individual coils being distinguished. In the aneurysms embolised with hydrogel filaments, visualisation of the individual coils, residual flow and stent with minor or no artefacts was possible using CTA. On the other hand, the beam hardening artefacts precluded analysis of aneurysms embolised with platinum coils.
CTA-compatible embolic devices could have wide applications in diverse locations throughout the vasculature, particularly in combination with stents or stent grafts.
我们通过数字减影血管造影术（DSA）和计算机断层血管造影术（CTA）比较了实验性兔颈动脉分叉动脉瘤用铂金线圈或水凝胶丝栓塞的效果。
使用铂金线圈（n = 2）、载碘水凝胶丝（n = 3）和载硫酸钡水凝胶丝（n = 3）进行栓塞。在一种情况下，在母血管中部署了支架以确定水凝胶丝对支架可视化的影响。DSA 评估在治疗后即刻进行。CTA 评估在治疗后 0-13 周进行。DSA 和 CTA 图像评估的指标为无伪影和栓塞物质、单个线圈和动脉瘤囊和颈部残留血流的可视性。
三组之间的 DSA 结果基本一致。栓塞物质很容易被发现，有些单个线圈也可以被区分。在用水凝胶丝栓塞的动脉瘤中，CTA 可以实现对单个线圈、残留血流和支架的轻微或无伪影的可视化。另一方面，由于束硬化伪影，无法对用铂金线圈栓塞的动脉瘤进行分析。
与 CTA 兼容的栓塞装置可以在血管系统的各种部位广泛应用，特别是与支架或支架移植结合使用。
