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[家庭医学中酒精中毒的诊断:密歇根酒精中毒筛查测试与血清γ-谷氨酰转移酶水平相关性的初步研究]

[The diagnosis of alcoholism in family medicine: a pilot study of the correlation of the Michigan Alcoholism Screening Test and the level of serum gamma-glutamyltransferase].

作者信息

Léouffre P J, Tempier R, Dongier M H

机构信息

Université de Montréal.

出版信息

CMAJ. 1990 Sep 15;143(6):504-6.

PMID:1976428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1452272/
Abstract

When used simultaneously, are laboratory and psychosocial methods of screening helpful to detect alcoholism in general practice? To examine this issue, systematic screening with a self-administered Michigan Alcoholism Screening Test and measurement of the plasma gamma-glutamyltransferase level was offered to 435 clients at a family medicine clinic. Whenever a positive finding was obtained the client was free to undergo a more detailed evaluation to confirm the diagnosis. A total of 200 subjects (126 women, 74 men) agreed to undergo screening. The results do not appear to lead to practical consequences among women, in whom no case was identified. In contrast, in the male population a rate of first detection of 9.5% (seven cases) should encourage such screening for alcoholism in family medicine.

摘要

在一般医疗实践中,同时使用实验室检查和心理社会筛查方法有助于检测酒精中毒吗?为了探讨这个问题,我们对一家家庭医学诊所的435名患者进行了系统筛查,采用自我管理的密歇根酒精中毒筛查测试,并测量血浆γ-谷氨酰转移酶水平。每当获得阳性结果时,患者可自行接受更详细的评估以确诊。共有200名受试者(126名女性,74名男性)同意接受筛查。结果似乎对女性没有实际影响,未发现一例病例。相比之下,在男性人群中,首次检测率为9.5%(7例),这应该会促使在家庭医学中对酒精中毒进行此类筛查。

相似文献

1
[The diagnosis of alcoholism in family medicine: a pilot study of the correlation of the Michigan Alcoholism Screening Test and the level of serum gamma-glutamyltransferase].[家庭医学中酒精中毒的诊断:密歇根酒精中毒筛查测试与血清γ-谷氨酰转移酶水平相关性的初步研究]
CMAJ. 1990 Sep 15;143(6):504-6.
2
Self-identification and the underdetection of alcoholism.自我认知与酒精中毒的漏诊
Dis Nerv Syst. 1975 Mar;36(3):133-6.
3
[The diagnostic validity of screening tests and laboratory markers in alcohol use disorders].[酒精使用障碍筛查试验和实验室标志物的诊断效度]
Turk Psikiyatri Derg. 2005 Spring;16(1):3-12.
4
Use of the self-administered Michigan Alcoholism Screening Test in a family practice center.在一家家庭医疗中心使用自行管理的密歇根酒精成瘾筛查测试。
J Fam Pract. 1983 Dec;17(6):1021-6.
5
Prevalence of alcoholism in a family practice center.一家家庭医疗中心的酗酒患病率。
J Fam Pract. 1984 Jun;18(6):867-70.
6
[Evaluation of an increased blood level of GGT, CDT, methanol, acetone and isopropanol in alcohol intoxicated automobile drivers. Alcoholism indicators instead of medical-psychological examination].[对酒精中毒汽车驾驶员血液中γ-谷氨酰转移酶、平均红细胞体积分布宽度、甲醇、丙酮和异丙醇水平升高的评估。用酒精中毒指标替代医学-心理检查]
Blutalkohol. 1994 Sep;31(5):273-314.
7
Drinkwatchers--description of subjects and evaluation of laboratory markers of heavy drinking.饮酒监测者——饮酒者的描述及重度饮酒实验室指标评估
Alcohol Alcohol. 1987;22(2):147-54.
8
Use of the Michigan alcoholism screening test in general practice.密歇根酒精中毒筛查测试在全科医疗中的应用。
J R Coll Gen Pract. 1986 Sep;36(290):409-10.
9
[Diagnostic value of carbohydrate-deficient transferrin, gamma-glutamyltransferase and mean erythrocyte volume as laboratory markers of chronic alcohol abuse].[缺糖转铁蛋白、γ-谷氨酰转移酶和平均红细胞体积作为慢性酒精滥用实验室标志物的诊断价值]
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The validity of the laboratory marker combinations DOVER and QUVER to detect physician's diagnosis of at-risk drinking.实验室标志物组合DOVER和QUVER用于检测医生诊断的高危饮酒的有效性。
Addict Biol. 2007 Mar;12(1):85-92. doi: 10.1111/j.1369-1600.2006.00049.x.

本文引用的文献

1
Validation of the Veterans Alcoholism Screening Test.退伍军人酒精中毒筛查测试的验证
J Stud Alcohol. 1982 Sep;43(9):910-26. doi: 10.15288/jsa.1982.43.910.
2
Early identification of alcohol abuse: 2: Clinical and laboratory indicators.酒精滥用的早期识别:2:临床和实验室指标。
Can Med Assoc J. 1981 May 15;124(10):1279-94, 1299.
3
Validity and reliability of the Michigan alcoholism screening test: a review.
Drug Alcohol Depend. 1983 Nov;12(3):279-85. doi: 10.1016/0376-8716(83)90071-6.
4
Comparison of questionnaire and laboratory tests in the detection of excessive drinking and alcoholism.问卷调查与实验室检测在过量饮酒及酒精中毒检测中的比较
Lancet. 1982 Feb 6;1(8267):325-8. doi: 10.1016/s0140-6736(82)91579-3.
5
A kinetic photometric method for serum gamma-glutamyl transpeptidase.一种测定血清γ-谷氨酰转肽酶的动力学光度法。
Clin Chem. 1969 Feb;15(2):124-36.
6
The Michigan alcoholism screening test: the quest for a new diagnostic instrument.密歇根酒精中毒筛查测试:对一种新型诊断工具的探索。
Am J Psychiatry. 1971 Jun;127(12):1653-8. doi: 10.1176/ajp.127.12.1653.
7
Depression of delta-aminolaevulic acid dehydrase activity by ethanol in man and rat.乙醇对人和大鼠δ-氨基乙酰丙酸脱水酶活性的抑制作用。
Clin Sci. 1971 Jan;40(1):81-8. doi: 10.1042/cs0400081.
8
The brief MAST: a shortened version of the Michigan Alcoholism Screening Test.简易MAST:密歇根酒精中毒筛查测试的简化版。
Am J Psychiatry. 1972 Sep;129(3):342-5. doi: 10.1176/ajp.129.3.342.
9
Serum -glutamyl transpeptidase activity in alcoholism.酗酒者血清γ-谷氨酰转肽酶活性
Clin Chim Acta. 1972 Jun;39(1):41-7. doi: 10.1016/0009-8981(72)90297-5.
10
The CAGE questionnaire: validation of a new alcoholism screening instrument.CAGE问卷:一种新型酒精中毒筛查工具的验证
Am J Psychiatry. 1974 Oct;131(10):1121-3. doi: 10.1176/ajp.131.10.1121.