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[家庭医学中酒精中毒的诊断:密歇根酒精中毒筛查测试与血清γ-谷氨酰转移酶水平相关性的初步研究]

[The diagnosis of alcoholism in family medicine: a pilot study of the correlation of the Michigan Alcoholism Screening Test and the level of serum gamma-glutamyltransferase].

作者信息

Léouffre P J, Tempier R, Dongier M H

机构信息

Université de Montréal.

出版信息

CMAJ. 1990 Sep 15;143(6):504-6.

Abstract

When used simultaneously, are laboratory and psychosocial methods of screening helpful to detect alcoholism in general practice? To examine this issue, systematic screening with a self-administered Michigan Alcoholism Screening Test and measurement of the plasma gamma-glutamyltransferase level was offered to 435 clients at a family medicine clinic. Whenever a positive finding was obtained the client was free to undergo a more detailed evaluation to confirm the diagnosis. A total of 200 subjects (126 women, 74 men) agreed to undergo screening. The results do not appear to lead to practical consequences among women, in whom no case was identified. In contrast, in the male population a rate of first detection of 9.5% (seven cases) should encourage such screening for alcoholism in family medicine.

摘要

在一般医疗实践中,同时使用实验室检查和心理社会筛查方法有助于检测酒精中毒吗?为了探讨这个问题,我们对一家家庭医学诊所的435名患者进行了系统筛查,采用自我管理的密歇根酒精中毒筛查测试,并测量血浆γ-谷氨酰转移酶水平。每当获得阳性结果时,患者可自行接受更详细的评估以确诊。共有200名受试者(126名女性,74名男性)同意接受筛查。结果似乎对女性没有实际影响,未发现一例病例。相比之下,在男性人群中,首次检测率为9.5%(7例),这应该会促使在家庭医学中对酒精中毒进行此类筛查。

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J Stud Alcohol. 1982 Sep;43(9):910-26. doi: 10.15288/jsa.1982.43.910.
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Serum -glutamyl transpeptidase activity in alcoholism.酗酒者血清γ-谷氨酰转肽酶活性
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