Moray G, Shahbazov R, Sevmis S, Karakayali H, Torgay A, Arslan G, Savas N, Yilmaz U, Haberal M
Department of General Surgery, Faculty of Medicine, Başkent University, Ankara, Turkey.
Transplant Proc. 2009 Sep;41(7):2936-8. doi: 10.1016/j.transproceed.2009.07.022.
Hepatic alveolar echinococcosis is an infectious disease caused by the larval stage of Echinococcus multilocularis, which grows primarily in the liver of an infected person and develops as a tumorlike lesion. In advanced cases, the organisms infiltrate every organ neighboring the liver and spread hematogenously to distant organs such as lungs and brain. Surgical resection and liver transplantation are accepted treatment options for early and advanced disease, respectively. Herein, we present case reports of 2 patients with advanced alveolar echinococcal disease that invaded both lobes of the liver and neighboring vital structures including the inferior vena cava. Despite the technical difficulty of the surgery, both patients were successfully treated with living donor liver transplantation. Liver transplantation should be accepted as a life-saving treatment of choice in patients with alveolar echinococcosis for whom there is no other medical or surgical treatment options.
肝泡型包虫病是由多房棘球绦虫幼虫阶段引起的一种传染病，主要生长在感染者的肝脏中，并发展为肿瘤样病变。在晚期病例中，病原体浸润肝脏邻近的每个器官，并通过血液扩散到远处的器官，如肺和脑。手术切除和肝移植分别是早期和晚期疾病公认的治疗选择。在此，我们报告2例晚期泡型包虫病患者的病例，病变侵犯了肝脏两叶及包括下腔静脉在内的邻近重要结构。尽管手术技术难度大，但两名患者均通过活体供肝移植成功治愈。对于没有其他内科或外科治疗选择的泡型包虫病患者，肝移植应被视为一种挽救生命的治疗选择。
