Maddah Ghodratollah, Abdollahi Abbas, Sharifi-Nooghabi Reza, Tavassoli Alireza, Rajabi-Mashadi Mohammad Taghi, Jabbari-Nooghabi Azadeh, Jabbari-Nooghabi Mehdi
Endoscopic and Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Caspian J Intern Med. 2016 Winter;7(1):52-6.
Alveolar echinococcosis (AE) is a chronic, rare and sometimes lethal parasitic infection in humans, caused by the larval stage of the fox tapeworm Echinococcus multilocularis. This study aimed to investigate the clinical aspects and treatment outcomes of patients with alveolar hydatid disease.
The medical records of patients with alveolar echinococcosis admitted between 1997 and 2012 were reviewed. Diagnosis was confirmed by physical examination, ultrasonography and CT scanning and MRI. Various treatment techniques were used such as complete liver resection in seven (38.89%) patients, biliary bypass in two (11.11%) patients, laparotomy and tumor biopsy in eight (44.44%) patients and long term medical treatment in one (5.56%) patient. After discharge, all patients were followed to determine the effect of treatment, complications, recurrences and survival.
A total of 18 patients with mean age of 46.11±15.14 years (range 23-74 years) were studied. The disease was more prevalent in women than men (78.9% vs 4, 21.1%, P=0.021). Fourteen (77.78%) patients live in Chenaran, a town located in Khorasan, Iran). Death occurred in (22.22%) patients after an average period of 45.70±7.50 months after disease onset. 14 remaining patients survived after a mean follow-up duration of 54.60±29.17 months.
Diagnosis of alveolar echinococcosis should be considered in endemic area. Early diagnosis and treatment is associated with excellent outcome.
泡型包虫病（AE）是一种人类慢性、罕见且有时致命的寄生虫感染，由狐绦虫多房棘球绦虫的幼虫阶段引起。本研究旨在调查泡型包虫病患者的临床情况及治疗结果。
回顾了1997年至2012年间收治的泡型包虫病患者的病历。通过体格检查、超声、CT扫描和MRI确诊。采用了多种治疗技术，如7例（38.89%）患者行肝全切术，2例（11.11%）患者行胆肠吻合术，8例（44.44%）患者行剖腹探查及肿瘤活检，1例（5.56%）患者进行长期药物治疗。出院后，对所有患者进行随访，以确定治疗效果、并发症、复发情况及生存率。
共研究了18例患者，平均年龄46.11±15.14岁（范围23 - 74岁）。女性患者比男性患者更易患病（78.9%对4例，21.1%，P = 0.021）。14例（77.78%）患者居住在伊朗霍拉桑省的切纳兰镇。22.22%的患者在疾病发作后平均45.70±7.50个月死亡。其余14例患者在平均随访54.60±29.17个月后存活。
在流行地区应考虑泡型包虫病的诊断。早期诊断和治疗与良好的预后相关。
