精神分裂症和双相情感障碍患者布罗德曼46区中神经调节蛋白1和3的蛋白水平。
Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder.
作者信息
Boer Simone, Berk Michael, Dean Brian
机构信息
The Rebecca L. Cooper Research Laboratories, The Mental Health Research Institute, Victoria 3052, Australia.
出版信息
Neurosci Lett. 2009 Nov 27;466(1):27-9. doi: 10.1016/j.neulet.2009.09.019. Epub 2009 Sep 17.
Neuregulin (NRG) 1Ialpha and NRG3 proteins levels were measured in Brodmann's area 46 from 20 subjects with schizophrenia, 8 subjects with bipolar 1 disorder and 20 age-sex matched control subjects. Protein levels of both NRG1Ialpha and NRG3 were unchanged in both psychiatric illnesses. These data suggest any change in NRG1Ialpha and NRG3 expression in schizophrenia or bipolar 1 disorder do not result in changes levels in levels of those proteins Brodmann's area 46.
在20名精神分裂症患者、8名双相I型障碍患者以及20名年龄和性别匹配的对照受试者的布罗德曼46区测量了神经调节蛋白（NRG）1α和NRG3的蛋白水平。在这两种精神疾病中，NRG1α和NRG3的蛋白水平均未改变。这些数据表明，精神分裂症或双相I型障碍中NRG1α和NRG3表达的任何变化都不会导致布罗德曼46区这些蛋白水平的改变。
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