Garza-Treviño E S, Volkow N D, Cancro R, Contreras S
University of Texas Health Science Center, San Antonio.
Hosp Community Psychiatry. 1990 Sep;41(9):971-80. doi: 10.1176/ps.41.9.971.
The development of imaging technologies for investigating the living human brain has expanded knowledge about schizophrenia and is providing clues about biological factors associated with the disorder. Drawing on these and other developments in the last two decades, the authors review selected structural, functional, neurochemical, immunological, and infectious factors associated with the schizophrenic syndrome. Many of the biological alterations reported have also been found in other psychiatric, neurological, and medical conditions; therefore, the findings have little specificity for schizophrenia and in fact support the heterogeneity of the disorder.
用于研究活体人类大脑的成像技术的发展，拓展了对精神分裂症的认识，并为与该疾病相关的生物学因素提供了线索。基于过去二十年的这些及其他进展，作者回顾了与精神分裂症综合征相关的选定的结构、功能、神经化学、免疫和感染因素。所报道的许多生物学改变在其他精神、神经和医学病症中也有发现；因此，这些发现对精神分裂症的特异性较低，实际上支持了该疾病的异质性。
