Department of Pathology and Clinical Propedeutics (Buccal Pathology), São Paulo State University - UNESP, Araçatuba, São Paulo, Brazil.
Med Oral Patol Oral Cir Bucal. 2010 Mar 1;15(2):e347-9. doi: 10.4317/medoral.15.e347.
Lipomas are benign mesenchymal neoplasms of soft tissue that can be found in any part of the human body. Conversely, their presence in the oral mucosa is rather uncommon, with approximately 4% of the cases occurring in the oral cavity. In such cases, they are likely to have originated from mature adipose tissue and to be among several described histological variants of lipomas, which are identified according to the predominant type of tissue. There is a rare lipoma, known as an osteolipoma or an ossifying lipoma; however, little has been written this type of lipoma characterized by a classical lipoma with areas of osseous metaplasia. Considering the few cases of oral osteolipomas previously described in the English-related literature and the consequent risk of misdiagnosis and overtreatment, this paper describes an extreme case of an osteolipoma affecting the buccal mucosa of an adult patient. This paper focuses particularly on the pathogenesis of this lesion and the discussion of a correct diagnosis.
脂肪瘤是一种良性的软组织间叶性肿瘤，可发生于人体的任何部位。相反，口腔黏膜中脂肪瘤较为少见，约占口腔内肿瘤的 4%。此类脂肪瘤可能来源于成熟的脂肪组织，属于脂肪瘤的几种描述性组织学变体之一，其依据主要组织类型来进行鉴别。有一种罕见的脂肪瘤，称为骨脂肪瘤或成骨性脂肪瘤；然而，对于这种具有典型脂肪瘤并伴有骨改建区域的脂肪瘤类型，相关文献报道较少。鉴于以往在英语文献中描述的口腔骨脂肪瘤病例较少，可能存在误诊和过度治疗的风险，本文报道了一例发生于成人颊黏膜的骨脂肪瘤的极罕见病例。本文重点介绍了该病变的发病机制，并对正确的诊断进行了讨论。
