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[Dietary intake and dyslipidemia arising from combination antiretroviral therapy for HIV infection: a systematic review].

作者信息

Almeida Luara Bellinghausen, Giudici Kelly Virecoulon, Jaime Patricia Constante

机构信息

Faculdade de Saúde Pública da Universidade de São Paulo (FSP/USP), São Paulo, SP, Brasil.

出版信息

Arq Bras Endocrinol Metabol. 2009 Jul;53(5):519-27. doi: 10.1590/s0004-27302009000500005.

DOI:10.1590/s0004-27302009000500005
PMID:19768243
Abstract

To review and synthesize the available scientific evidence on the relationship between dietary intake and dyslipidemias in HIV-infected patients in combination antiretroviral therapy (ART). A systematic review of literature was carried out. Original and published studies were investigated and two categories of dietary exposure were considered: energy and nutrient intake, and consumption of a test diet. A narrative review of included studies was conducted. The findings were summarized according to category of metabolic outcomes (effect on total cholesterol and LDL-c, effect on HDL-c and effect on triglycerides). Twenty original studies were included in this review, being 13 clinical trials and 7 observational studies. Omega-3 fatty acid supplementation led to a significant decrease in triglycerides. There was very little evidence on the effectiveness of dietary interventions for the prevention and control of dyslipidemias in HIV-infected patients receiving ART.

摘要

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