Iurenev A P, Lediashova G A, Lupanov V P, Rubanovich A I, Zhukova I M
Kardiologiia. 1990 Jun;30(6):47-51.
The paper analyses the results of a 10-year prospective study of 396 patients with coronary heart disease concurrent with stable angina pectoris of different functional classes without serious concomitant diseases. In all the patients. coronary angiography revealed stenosis of one-to-three great coronary arteries and ventriculography showed no severe abnormalities in left ventricular contractility. A long-term drug therapy promoted not only improvement of the clinical status in most patients, but maintenance of work capacity and increase of their lifespan. The annual mortality rate was 3.0%, the incidence of nonfatal myocardial infarction was 5.9%. Repeated coronary angiography indicated that progression of coronary atherosclerosis was accompanied by a clinical deterioration in the patients' health and a decrease in exercise tolerance.
本文分析了一项针对396例冠心病合并不同功能分级稳定型心绞痛且无严重伴随疾病患者的10年前瞻性研究结果。在所有患者中，冠状动脉造影显示一至三支主要冠状动脉狭窄，心室造影显示左心室收缩功能无严重异常。长期药物治疗不仅使大多数患者的临床状况得到改善，还维持了工作能力并延长了寿命。年死亡率为3.0%，非致命性心肌梗死发生率为5.9%。重复冠状动脉造影表明，冠状动脉粥样硬化进展伴随着患者健康状况的临床恶化和运动耐量下降。
