Lupanov V P, Sidorenko B A, Nekrutman E A, Kulikova T V, Podinovskaia Ia A
Kardiologiia. 1987 Mar;27(3):23-9.
The results of 5-year pharmacologic treatment of 234 coronary patients with stable angina of varying functional classes are reported. Coronarography detected stenosis of major coronary arteries in all cases; ventriculography demonstrated no disorders of left-ventricular contractility. Clinical improvement and stabilization occurred in 75.2% of patients, deterioration, in 24.8%. Of the latter group, nonfatal myocardial infarction occurred in 13.7%, and signs of heart failure developed in 9.8%. Repeat bicycle ergometry demonstrated increased or unchanged physical stress tolerance in 67.1%. Working capacity was intact after five years in 61.1%. Therefore, long-term medication of coronary patients with stable angina and normal left-ventricular contractility has proved efficient.
报告了对234例不同功能分级的稳定型心绞痛冠心病患者进行5年药物治疗的结果。冠状动脉造影在所有病例中均检测到主要冠状动脉狭窄；心室造影显示左心室收缩功能无异常。75.2%的患者临床症状改善并稳定，24.8%的患者病情恶化。在后一组中，13.7%发生了非致命性心肌梗死，9.8%出现了心力衰竭迹象。重复进行的自行车测力计测试表明，67.1%的患者身体应激耐量增加或不变。61.1%的患者在5年后工作能力保持完好。因此，对左心室收缩功能正常的稳定型心绞痛冠心病患者进行长期药物治疗已被证明是有效的。
