“干细胞”概念：它在阻碍我们吗？
The 'stem cell' concept: is it holding us back?
作者信息
Lander Arthur D
机构信息
Center for Complex Biological Systems, Department of Developmental and Cell Biology, and Department of Biomedical Engineering, University of California at Irvine, Irvine, CA 92697-2300, USA.
出版信息
J Biol. 2009 Sep 21;8(8):70. doi: 10.1186/jbiol177.
Abstract
Developmental biology, regenerative medicine and cancer biology are increasingly occupied with the molecular characterization of stem cells. Yet recent work adds to a growing body of literature suggesting that 'stemness' cannot be reduced to the molecular features of cell types, and is instead an emergent property of cell lineages under feedback control.
摘要
发育生物学、再生医学和癌症生物学越来越关注干细胞的分子特征。然而，最近的研究增加了越来越多的文献表明，“干性”不能简化为细胞类型的分子特征，而是反馈控制下细胞谱系的一种涌现特性。
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