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脑瘫患者痉挛状态的外科治疗

Surgical management of spasticity in persons with cerebral palsy.

作者信息

Lynn Abigail K, Turner Michael, Chambers Henry G

机构信息

Rady Children's Hospital, University of California San Diego, San Diego, CA 92123, USA.

出版信息

PM R. 2009 Sep;1(9):834-8. doi: 10.1016/j.pmrj.2009.07.016.

Abstract

Cerebral palsy is a disorder that primarily affects the neurologic system but secondarily affects the musculoskeletal system through the effects of spasticity, dystonia, and other movement disorders. The treatment of cerebral palsy requires a multidisciplinary approach with treatment aimed at modulating the movement disorder through oral medication, injectable drugs (phenol, botulinum toxin), and physical and occupational therapy. Treatment of the neurologic effects of the central movement disorders include selective dorsal rhizotomy, intrathecal baclofen pump placement, and potentially deep brain stimulation. Although any effect on tone is temporary, orthopedic surgery has an important role in the treatment of the musculoskeletal deformities and contractures present in the child with cerebral palsy. Orthopedic surgery improves function by lengthening the musculotendinous structures, transferring tendons, performing osteotomies to reduce dislocated joints, and normalizing rotation and fusion of selected joints to improve stability. Neurosurgical techniques are not as widely used, but may reduce spasticity in select individuals. The combined approach of managing tone and normalizing the biomechanics of the spine and upper and lower extremities through orthopedic surgery and neurosurgery and subsequent rehabilitation is the cornerstone of treatment of the child and adult with cerebral palsy.

摘要

脑瘫是一种主要影响神经系统,但其次通过痉挛、肌张力障碍和其他运动障碍影响肌肉骨骼系统的疾病。脑瘫的治疗需要多学科方法,治疗旨在通过口服药物、注射药物(苯酚、肉毒杆菌毒素)以及物理和职业治疗来调节运动障碍。中枢运动障碍的神经学影响的治疗包括选择性背根切断术、鞘内注射巴氯芬泵植入,以及可能的深部脑刺激。尽管对肌张力的任何影响都是暂时的,但骨科手术在治疗患有脑瘫的儿童出现的肌肉骨骼畸形和挛缩方面具有重要作用。骨科手术通过延长肌腱结构、转移肌腱、进行截骨术以减少脱位关节,以及使选定关节的旋转和融合正常化以提高稳定性来改善功能。神经外科技术使用并不广泛,但可能会减轻部分患者的痉挛。通过骨科手术和神经外科手术以及随后的康复来控制肌张力并使脊柱和上下肢的生物力学正常化的综合方法是治疗儿童和成人脑瘫的基石。

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