Valdes-Socin H, Niaourou V, Vandeva S, Bosquée L, Beckers A
Service d'endocrinologie, CHU Sart Tilman, 4000 Liège, Belgique.
Rev Med Suisse. 2009 Aug 26;5(214):1668-74.
Paraneoplastic endocrine syndromes define a group of secondary signs and symptoms associated to a neoplasia, independently from the location of the primary tumor or its metastases. Paraneoplastic or ectopic endocrine syndromes usually result from aberrant hormone precursors or hormone-like substances by tumours. Knowledge of paraneoplastic endocrine complications is important both for the early diagnosis of neoplasia and the prognosis of the patient. In this review we discuss almost all reported paraneoplastic endocrine syndromes. We analyze their prevalence, etiology, laboratory diagnosis and treatment.
副肿瘤性内分泌综合征是指一组与肿瘤相关的继发性体征和症状，与原发性肿瘤或其转移灶的位置无关。副肿瘤性或异位内分泌综合征通常由肿瘤产生的异常激素前体或类激素物质引起。了解副肿瘤性内分泌并发症对于肿瘤的早期诊断和患者的预后都很重要。在这篇综述中，我们讨论了几乎所有已报道的副肿瘤性内分泌综合征。我们分析了它们的患病率、病因、实验室诊断和治疗方法。
