Toumba K J, Al-Ibrahim N S, Curzon M E J
Department of Paediatric Dentistry, Leeds Dental Institute, Clarendon Way, Leeds, UK.
Eur Arch Paediatr Dent. 2009 Sep;10(3):175-82. doi: 10.1007/BF03262680.
Fluoride has been used to combat dental caries using a number of different clinical approaches. An exciting relatively new development is fluoride slow-releasing devices that consistently elevate intra-oral fluoride levels of plaque and saliva for prolonged periods of up to two years.
The literature on the use of slow-releasing fluoride devices in dentistry were reviewed. A Medline search on key words was carried out. All papers in English were individually reviewed.
Slow-releasing fluoride devices have been shown to be effective in elevating salivary fluoride levels in both animals and human studies and to enhance the remineralisation of dental enamel. They have been demonstrated to be safe to use and without the risk of fluoride toxicity. A double blind randomised clinical trial demonstrated 76% fewer new carious surface increment in high caries-risk children after two years.
These devices have a number of potential uses in dentistry and in particular have great potential for caries prevention of non-compliant high caries-risk groups.
氟化物已被用于通过多种不同的临床方法防治龋齿。一个令人兴奋的相对较新的进展是氟化物缓释装置,它能持续两年长时间提高口腔内菌斑和唾液中的氟化物水平。
对牙科中使用氟化物缓释装置的文献进行了综述。通过关键词在Medline上进行了检索。对所有英文论文进行了逐一审阅。
在动物和人体研究中,氟化物缓释装置均已证明能有效提高唾液氟化物水平,并增强牙釉质的再矿化。已证明其使用安全,无氟中毒风险。一项双盲随机临床试验表明,两年后高龋齿风险儿童的新龋面增量减少了76%。
这些装置在牙科有许多潜在用途,尤其在预防不配合治疗的高龋齿风险人群的龋齿方面有很大潜力。