Frobisher Clare, Lancashire Emma R, Winter David L, Taylor Aliki J, Reulen Raoul C, Hawkins Michael M
Centre for Childhood Cancer Survivor Studies (CCCSS), School of Health and Population Sciences, Public Health Building, University of Birmingham, Edgbaston, Birmingham, UK.
Pediatr Blood Cancer. 2010 Jan;54(1):116-22. doi: 10.1002/pbc.22290.
Previously from the British Childhood Cancer Survivor Study (BCCSS) it was seen that adult survivors of childhood cancer were less likely to marry than the general population. The objectives of this study were to assess the number of childhood cancer survivors from the BCCSS who were currently divorced or separated, examine factors associated with marriage dissolution and compare survivor divorce rates to population rates.
The BCCSS is a population-based cohort of 18,119 individuals diagnosed with cancer aged 0-14 years between 1940 and 1991, and survived at least 5 years. 14,539 were alive, aged 16 years or over and eligible to receive a questionnaire, which ascertained marital status.
From 8,155 survivors, who were aged at least 20 years at questionnaire completion, the proportions currently divorced and divorced or separated were 13.5% and 18.1%, respectively. Only current age, educational attainment and age at marriage were associated with divorce, and for divorce and separation status only age at marriage (P < 0.05). Overall the survivors were no different to the general population for being currently divorced (odds ratio (OR) (95% confidence intervals (95% CI)): 0.94 (0.81-1.10)). However, the survivors overall (OR (95% CI): 0.82 (0.72-0.94)), and separately for those diagnosed with non-Hodgkin lymphoma (OR (95% CI): 0.55 (0.34-0.89)) and leukaemia (OR (95% CI): 0.70 (0.52-0.95)), were less likely to be currently divorced or separated than the general population.
It is reassuring that survivors do not experience more divorce than the general population, and that no cancer or treatment factors were shown to be associated with marriage dissolution.
先前英国儿童癌症幸存者研究（BCCSS）显示，儿童癌症成年幸存者结婚的可能性低于普通人群。本研究的目的是评估BCCSS中目前离婚或分居的儿童癌症幸存者数量，研究与婚姻解体相关的因素，并将幸存者的离婚率与总体人群的离婚率进行比较。
BCCSS是一个基于人群的队列研究，研究对象为1940年至1991年间确诊患癌的18119名0至14岁个体，且存活至少5年。其中14539人存活，年龄在16岁及以上，有资格收到一份询问婚姻状况的问卷。
在问卷完成时年龄至少20岁的8155名幸存者中，目前离婚者的比例为13.5%，离婚或分居者的比例为18.1%。只有当前年龄、教育程度和结婚年龄与离婚有关，而对于离婚和分居状况，只有结婚年龄相关（P<0.05）。总体而言，幸存者目前离婚的情况与普通人群没有差异（优势比（OR）（95%置信区间（95%CI））：0.94（0.81-1.10））。然而，总体幸存者（OR（95%CI）：0.82（0.72-0.94）），以及分别被诊断为非霍奇金淋巴瘤（OR（95%CI）：0.55（0.34-0.89））和白血病的幸存者（OR（95%CI）：0.70（0.52-0.95）），目前离婚或分居的可能性低于普通人群。
令人安心的是，幸存者的离婚情况并不比普通人群更严重，且没有癌症或治疗因素与婚姻解体相关。
