Frobisher Clare, Lancashire Emma R, Winter David L, Jenkinson Helen C, Hawkins Michael M
CCCSS, Department of Public Health and Epidemiology, University of Birmingham, Edgbaston, B15 2TT, United Kingdom.
Int J Cancer. 2007 Aug 15;121(4):846-55. doi: 10.1002/ijc.22742.
The objectives of this study were to assess the number of adult survivors of childhood cancer who ever married and the factors influencing marriage, compare observed marriages to those expected from the general population, and assess age at marriage and influencing factors. The data is based on the British Childhood Cancer Survivor Study (BCCSS), which is a population-based cohort of 18,119 individuals who were diagnosed with childhood cancer between 1940 and 91 and survived at least 5 years. Fourteen thousand five hundred thirty-nine were alive, aged at least 16 years and eligible to receive a postal questionnaire, which ascertained marriage status. Thirty-four percent of 9,954 survivors had married. Survivors with the following characteristics: males, CNS neoplasm, received radiotherapy, diagnosed with mental retardation, registered blind, low social functioning score (calculated from SF-36 health status measure), and achieved the highest level of educational attainment, were less likely to have married than the complementary survivor groups. The deficits in the proportion ever married compared to the general population were mostly between 9 and 18% among males and 7-10% among females. The largest ever married deficits were among male CNS neoplasm survivors aged 30 years or over (29-38%). Age at first marriage among survivors was related to: sex, childhood cancer type, age at diagnosis, chemotherapy, radiotherapy, mental retardation, and level of educational attainment. Regular follow-up for these survivors should address not just physical late-effects of the childhood cancer and treatment, but also psychosocial needs throughout the lifespan of the survivors to help them achieve life events as they occur in the general population.
本研究的目的是评估 childhood cancer 的成年幸存者中曾经结婚的人数以及影响婚姻的因素,将观察到的婚姻情况与从一般人群中预期的情况进行比较,并评估结婚年龄及影响因素。数据基于英国儿童癌症幸存者研究(BCCSS),这是一个基于人群的队列,包含18119名在1940年至1991年期间被诊断为儿童癌症且存活至少5年的个体。一万四千五百三十九人在世,年龄至少16岁且有资格收到邮政问卷,该问卷确定了婚姻状况。9954名幸存者中有34%已婚。具有以下特征的幸存者:男性、中枢神经系统肿瘤、接受过放疗、被诊断为智力迟钝、登记为盲人、社会功能得分低(根据SF - 36健康状况测量计算)以及达到最高教育程度水平的,比其他幸存者组结婚的可能性更小。与一般人群相比,曾经结婚比例的不足在男性中大多在9%至18%之间,在女性中为7%至10%。曾经结婚比例不足最大的是30岁及以上的男性中枢神经系统肿瘤幸存者(29% - 38%)。幸存者的初婚年龄与以下因素有关:性别、儿童癌症类型、诊断年龄、化疗、放疗、智力迟钝以及教育程度水平。对这些幸存者的定期随访不仅应关注儿童癌症和治疗的身体晚期效应,还应关注幸存者整个生命周期的心理社会需求,以帮助他们实现像一般人群中那样的人生大事。