[获取用于腺病毒感染诊断的组特异性荧光免疫球蛋白]

[Obtaining group-specific fluorescent immunoglobulin for diagnosis of adenovirus infection].

作者信息

Matskevich A L, Lanskaia T I, Erilova S P, Blizniuk V V, Stanislavskaia V K

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1977 Jun(6):67-9.

PMID:197755

Abstract

The authors present the results of a comparative study of several schemes of rabbit immunization with mixtures consisting of 4 and 7 (mixture No. 1) nad 2, 4, and 7 (mixture No. 2) adenovirus types for the purpose of obtaining group-specific fluorescent immunoglobulins. Since a direct correlative dependence of the activity of fluorescent immunoglobulins on the antibody level to the adenoviruses of homologous type was revealed in the immune sera a combined scheme of mixture No. 2 administration was elaborated for the immunization of animals.

摘要

作者展示了一项比较研究的结果，该研究针对由4型和7型腺病毒（混合物1号）以及2型、4型和7型腺病毒（混合物2号）组成的混合物对兔子进行免疫的几种方案，目的是获得组特异性荧光免疫球蛋白。由于在免疫血清中发现荧光免疫球蛋白的活性与针对同源型腺病毒的抗体水平存在直接相关性，因此制定了一种联合使用混合物2号的方案用于动物免疫。