与痴呆相关的前角细胞变性和布尼纳型包涵体。
Anterior horn cell degeneration and Bunina-type inclusions associated with dementia.
作者信息
Hart M N, Cancilla P A, Frommes S, Hirano A
出版信息
Acta Neuropathol. 1977 Jun 15;38(3):225-8. doi: 10.1007/BF00688069.
PMID:197771
Abstract
The ultrastructural features of Bunina type inclusions in the anterior horn cells of a patient dying of amyotrophic lateral sclerosis with dementia appear unique. The Bunina-type inclusions are electron dense aggregates containing, and surrounded by organelle-like membranes. These inclusions appear to be a special type of autophagic vacuole, possibly arising from altered mitochondria.
摘要
在死于肌萎缩侧索硬化症合并痴呆症患者的前角细胞中，布尼纳型包涵体的超微结构特征显得独特。布尼纳型包涵体是电子致密聚集体，含有类细胞器膜并被其包围。这些包涵体似乎是一种特殊类型的自噬泡，可能源于线粒体的改变。
Zotero 插件