一名晚期成人型睾丸颗粒细胞瘤患者对抗血管生成治疗的反应。
Response to antiangiogenesis therapy in a patient with advanced adult-type testicular granulosa cell tumor.
作者信息
Harrison Michael R, Huang Wei, Liu Glenn, Gee Jason
机构信息
Section of Hematology/Oncology, Department of Medicine, University of Wisconsin, UW Carbone Cancer Center, Madison, Wisconsin, USA.
出版信息
Oncology (Williston Park). 2009 Aug;23(9):792-5.
Abstract
As granulosa cell tumors of the adult type are extremely uncommon testicular neoplasms, relatively few case reports and case series have been published. Treatment for localized, small-volume, or oligometastatic disease is generally surgical resection alone. Visceral or widely metastatic disease is relatively rare, so there is no consensus approach to treatment. We report the case of an advanced granulosa cell tumor of the testis with a confirmed partial response to an angiogenesis inhibitor after initial resistance to cytotoxic chemotherapy.
摘要
由于成人型颗粒细胞瘤是极其罕见的睾丸肿瘤，已发表的病例报告和病例系列相对较少。对于局限性、小体积或寡转移性疾病，通常仅采用手术切除治疗。内脏或广泛转移性疾病相对罕见，因此在治疗方法上尚无共识。我们报告了一例晚期睾丸颗粒细胞瘤病例，该病例在对细胞毒性化疗最初耐药后，对一种血管生成抑制剂有确证的部分缓解。
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