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睾丸成人型颗粒细胞瘤:一例报告并文献复习

Adult-type granulosa cell tumor of the testis: report of a case and review of literature.

作者信息

Elbachiri Meriem, Taleb Amina, Derrabi Nora, Bouchbika Zineb, Benchakroun Nadia, Jouhadi Hassan, Tawfiq Nezha, Sahraoui Souha, Benider Abdellatif

机构信息

Mohamed VI Center of Cancer Treatment, Morocco.

Service d'Anatomie Pathologique, Chu Ibnou Rochd, Casablanca, Morocco.

出版信息

Pan Afr Med J. 2017 Apr 4;26:198. doi: 10.11604/pamj.2017.26.198.11523. eCollection 2017.

Abstract

Granulosa cell tumors is classified into juvenile and adult types and comprise less than 5% of ovarian tumors in women and are much rarer in men which only 45 have been previously reported. We report here a 40-year young man with a left testicular adult type granulosa cell tumor. The tumor measured 5.5X5X4cm; Immunohistochemical stains showed the tumor diffusely positive for inhibin and vimentin. Post operative CT scans shows a lomboaortic lymphnodes treated by four cycles of chemotherapy type BEP (bleomycin, etoposide, cisplatin). The thoraco abdominal CT scans post chemotherapy shows the disappearance of the right testicular nodule and the lomboaortic lymphnodes. 2 years after treatment, the patient is alive and well with no signs of recurrence. Our report highlights one more case of this very rare tumor of the testis, which is quite problematic In terms of prognosis and management, and for this reason seems to have attracted the interest of many researchers recently.

摘要

颗粒细胞瘤分为幼年型和成年型,在女性卵巢肿瘤中占比不到5%,在男性中更为罕见,此前仅报道过45例。我们在此报告一名40岁的年轻男性患有左侧睾丸成年型颗粒细胞瘤。肿瘤大小为5.5×5×4厘米;免疫组化染色显示肿瘤抑制素和波形蛋白弥漫性阳性。术后CT扫描显示经四个周期BEP(博来霉素、依托泊苷、顺铂)化疗治疗的腰主动脉旁淋巴结。化疗后的胸腹部CT扫描显示右侧睾丸结节和腰主动脉旁淋巴结消失。治疗两年后,患者健在,无复发迹象。我们的报告再次强调了这种非常罕见的睾丸肿瘤病例,其在预后和管理方面颇具问题,因此最近似乎引起了许多研究人员的关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e743/5483374/568d6ae3704f/PAMJ-26-198-g001.jpg

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