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马圆线虫:生物学、临床意义及治疗综述

Equine cyathostomins: a review of biology, clinical significance and therapy.

作者信息

Corning Susan

机构信息

Fort Dodge Animal Health Italy, Via G, Amendola, 8, 40121 Bologna, Italy.

出版信息

Parasit Vectors. 2009 Sep 25;2 Suppl 2(Suppl 2):S1. doi: 10.1186/1756-3305-2-S2-S1.

Abstract

The small strongyles of horses, also known as cyathostomins, are considered the most prevalent and pathogenic parasites of horses today. The clinical syndrome of larval cyathostominosis which occurs as a result of mass emergence of inhibited stages has a high fatality rate despite the best standard of care given to affected horses. Management of the challenge level of cyathostomins to prevent the syndrome is preferable. Many different management programmes have been tried over the past two decades, with mixed success. Programmes have relied heavily on repeated use of anthelmintic treatments throughout the life of a horse. The widespread incidence of resistance to certain anthelmintics is reducing these options. An understanding of the biology of cyathostomins, risk factors for infection and appropriate strategic use of still effective anthelmintics is essential for the future management of this parasite group. This review highlights the necessity to use currently available anthelmintics that are appropriately suited to the biology of cyathostomins, and to maintain heir efficacy through an appropriate treatment strategy.

摘要

马的小型圆线虫,也被称为杯冠属线虫,被认为是当今马类中最普遍且致病性最强的寄生虫。由抑制期大量出现导致的幼虫杯冠属线虫病临床综合征,尽管给予患病马匹最佳的标准护理,其死亡率仍很高。最好对杯冠属线虫的感染水平进行管理以预防该综合征。在过去二十年中尝试了许多不同的管理方案,但成效不一。这些方案严重依赖于在马的一生中反复使用驱虫治疗。对某些驱虫药产生抗药性的广泛发生正在减少这些选择。了解杯冠属线虫的生物学特性、感染的风险因素以及合理策略性地使用仍然有效的驱虫药对于未来管理这一寄生虫群体至关重要。本综述强调了使用目前可用的、适合杯冠属线虫生物学特性的驱虫药,并通过适当的治疗策略维持其疗效的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3e8/2751837/ed4e4a20b6a4/1756-3305-2-S2-S1-1.jpg

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