Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
J Vet Intern Med. 2009 Nov-Dec;23(6):1220-6. doi: 10.1111/j.1939-1676.2009.0393.x. Epub 2009 Sep 22.
Magnetic resonance imaging (MRI) is a correlate to physical examination in various myelopathies and a predictor of functional outcome.
To describe associations among MRI features, neurological dysfunction before MRI, and functional outcome in dogs with disk herniation.
One hundred and fifty-nine dogs with acute thoracolumbar disk herniation.
Retrospective case series. Signalment, initial neurological function as assessed by a modified Frankel score (MFS), and ambulatory outcome at hospital discharge and >3 months (long-term) follow-up were recorded from medical records and telephone interview of owners. Associations were estimated between these parameters and MRI signal and morphometric data.
Dogs with intramedullary T2W hyperintensity had more severe pre-MRI MFS (median 2, range 0-4) and lower ambulatory proportion at long-term follow-up (0.76) than those dogs lacking hyperintensity (median MFS 3, range 0-5; ambulatory proportion, 0.93) (P=.001 and .013, respectively). Each unit of T2W length ratio was associated with a 1.9 times lower odds of long-term ambulation when adjusted for pre-MRI MFS (95% confidence interval 1.0-3.52, P=.05). Dogs with a compressive length ratio >1.31 (which was the median ratio within this population) had more severe pre-MRI MFS (median 3, range 0-5) compared with those with ratios < or =1.31 (median MFS 3, range 0-4; P=.006).
MRI features were associated with initial injury severity in dogs with thoracolumbar disk herniation. Based on results of this study, the T2W length ratio and presence of T2W intramedullary hyperintensity appear to be predictive of long-term ambulatory status.
磁共振成像（MRI）是各种脊髓病的体格检查的相关检查，也是功能预后的预测指标。
描述椎间盘突出症犬的 MRI 特征、MRI 检查前神经功能障碍与功能预后之间的关系。
159 只患有急性胸腰椎间盘突出症的犬。
回顾性病例系列研究。从病历和对犬主人的电话访谈中记录了一般信息、改良的 Frankel 评分（MFS）评估的初始神经功能以及出院时和>3 个月（长期）随访时的活动能力。评估了这些参数与 MRI 信号和形态测量数据之间的相关性。
存在脊髓内 T2W 高信号的犬在 MRI 检查前的 MFS 评分更严重（中位数 2，范围 0-4），且在长期随访时的活动能力较低（比例 0.76），而缺乏高信号的犬（中位数 MFS 评分 3，范围 0-5；活动能力比例 0.93）（P=0.001 和.013）。在校正 MRI 检查前的 MFS 评分后，每个 T2W 长度比单位与长期活动能力降低的几率呈 1.9 倍相关（95%置信区间 1.0-3.52，P=0.05）。长度比>1.31（该人群中位数比值）的犬在 MRI 检查前的 MFS 评分更严重（中位数 3，范围 0-5），而长度比≤1.31 的犬（中位数 MFS 评分 3，范围 0-4；P=0.006）。
MRI 特征与胸腰椎间盘突出症犬的初始损伤严重程度相关。基于本研究的结果，T2W 长度比和 T2W 脊髓内高信号的存在似乎可以预测长期活动能力。
