Wooten Karen
Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
Phys Med Rehabil Clin N Am. 2009 Nov;20(4):657-76. doi: 10.1016/j.pmr.2009.06.011.
Diabetic peripheral neuropathy (DPN) is a common disorder that can lead to limb loss and death. Up to 50% of DPN patients can be asymptomatic. This fact contributes to making DPN the leading cause of lower limb amputation. The degree of heterogeneity in the clinical manifestations of DPN makes diagnosing this condition difficult. This article reviews the characteristics, diagnosis, electrodiagnosis, classification, pathogenesis, and treatment of DPN.
糖尿病周围神经病变（DPN）是一种常见疾病，可导致肢体丧失和死亡。高达50%的DPN患者可能无症状。这一事实使得DPN成为下肢截肢的主要原因。DPN临床表现的异质性程度使得诊断该病较为困难。本文综述了DPN的特征、诊断、电诊断、分类、发病机制及治疗。
