Satoh Yoshihide, Ishizuka Ken'Ichi, Murakami Toshiki
Department of Physiology, The Nippon Dental University School of Life Dentistry at Niigata, 1-8 Hamaura-cho, Chuou-ku, Niigata 951-8580, Japan.
Neurosci Lett. 2009 Nov 27;466(1):16-20. doi: 10.1016/j.neulet.2009.09.034. Epub 2009 Sep 23.
The effect of stimulation of the vestibular nuclear complex (VN) on the masseteric monosynaptic reflex (MMR) was studied in anesthetized rats. The MMR was evoked by electrical stimulation of the mesencephalic trigeminal nucleus and was recorded, bilaterally, as the electromyographic responses of the masseter muscles. Conditioning electrical stimulation of the medial vestibular nucleus (MVN) facilitated the MMR bilaterally, as did microinjection of monosodium glutamate into the MVN. In contrast, conditioning electrical stimulation of the inferior vestibular nucleus (IVN) inhibited the MMR bilaterally. Microinjection of monosodium glutamate into the IVN also inhibited the MMR bilaterally. Conditioning electrical stimulation of the lateral and superior vestibular nuclei did not modulate the MMR. These results suggest that the MVN and the IVN are involved in modulation of the MMR and plays an important role in controlling jaw movements.
在麻醉大鼠中研究了刺激前庭神经核复合体（VN）对咬肌单突触反射（MMR）的影响。通过电刺激中脑三叉神经核诱发MMR，并双侧记录咬肌的肌电图反应作为MMR。内侧前庭核（MVN）的条件性电刺激双侧促进了MMR，向MVN内微量注射谷氨酸钠也有同样效果。相反，下前庭核（IVN）的条件性电刺激双侧抑制了MMR。向IVN内微量注射谷氨酸钠也双侧抑制了MMR。外侧和上前庭核的条件性电刺激未调节MMR。这些结果表明，MVN和IVN参与了MMR的调节，并在控制下颌运动中起重要作用。
