枯草芽孢杆菌中伴侣蛋白酶系统在调控和蛋白质质量控制中的作用。
Chaperone-protease systems in regulation and protein quality control in Bacillus subtilis.
机构信息
Institut für Biologie-Mikrobiologie, Fachbereich Biologie, Chemie, Pharmazie, FU Berlin Königin-Luise-Str. 12-16, 14195 Berlin, Germany.
出版信息
Res Microbiol. 2009 Nov;160(9):637-44. doi: 10.1016/j.resmic.2009.08.020. Epub 2009 Sep 23.
The Gram-positive model organism Bacillus subtilis is extremely well adapted to changing environmental conditions. The chaperone-protease ClpCP and other AAA+ proteases constitute an important component of the B. subtilis protein quality control system that is essential for survival during stress. In this review, we discuss recent discoveries concerning the molecular mechanism, regulation and localization of proteases and chaperones in B. subtilis.
革兰氏阳性模式生物枯草芽孢杆菌极其适应环境条件的变化。伴侣蛋白酶 ClpCP 和其他 AAA+ 蛋白酶构成了枯草芽孢杆菌蛋白质质量控制系统的重要组成部分，对于应激期间的生存至关重要。在这篇综述中，我们讨论了关于枯草芽孢杆菌中蛋白酶和伴侣蛋白的分子机制、调控和定位的最新发现。
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