LaGrenade L, Hanchard B, Fletcher V, Cranston B, Blattner W
Department of Medicine, University of the West Indies, Mona, Jamaica.
Lancet. 1990 Dec 1;336(8727):1345-7. doi: 10.1016/0140-6736(90)92896-p.
In Jamaican children infective dermatitis is a chronic eczema associated with refractory nonvirulent Staphylococcus aureus or beta-haemolytic streptococcus infection of the skin and nasal vestibule. 14 children between the ages of 2 and 17 years with typical infective dermatitis, attending the dermatology clinic at the University Hospital of the West Indies in Jamaica, were tested for antibody to human T-lymphotropic virus type 1 (HTLV-1). All were seropositive, whereas 11 children of similar age with atopic eczema were all negative. In 2 of 2 cases of infective dermatitis, the biological mother was HTLV-1 seropositive. None of the 14 patients showed signs of adult T-cell leukaemia/lymphoma, though experience with previous cases of infective dermatitis indicates the possibility of such progression.
在牙买加儿童中，感染性皮炎是一种慢性湿疹，与皮肤和鼻前庭的难治性非致病性金黄色葡萄球菌或β-溶血性链球菌感染有关。在牙买加西印度群岛大学医院皮肤科门诊就诊的14名年龄在2至17岁之间患有典型感染性皮炎的儿童，接受了抗人类嗜T淋巴细胞病毒1型（HTLV-1）抗体检测。所有患儿血清学均呈阳性，而11名年龄相仿的特应性皮炎患儿均为阴性。在2例感染性皮炎患儿中，其生母HTLV-1血清学呈阳性。尽管以往感染性皮炎病例的经验表明有这种进展的可能性，但这14名患者均未表现出成人T细胞白血病/淋巴瘤的迹象。
