Department of Kinesiology, Pennsylvania State University, USA.
Maturitas. 2009 Dec 20;64(4):235-40. doi: 10.1016/j.maturitas.2009.09.007. Epub 2009 Sep 24.
To determine whether depressed mood and fatigue mediate the relationships between physical activity, body mass index, menopausal hot flashes, and perceived stress.
This study is a secondary analysis of data obtained from a sub-sample of peri- and postmenopausal women (N=212) from the TREMIN Research Program on Women's Health.
The hypothesized mediational model was tested using path analysis within a structural equation modeling framework in Mplus Version 5.1. In unadjusted analysis, the relationships between physical activity, menopausal hot flashes, and perceived stress were mediated by depressed mood; fatigue mediated the relationships between hot flashes, body mass index, and perceived stress. When adjusting for age, insomnia, menopausal and hormone use status, the mediational effects of depressed mood on stress remained significant only for physical activity, and fatigue mediated the relationship between hot flashes and stress. The adjusted model explained 70% of variance in perceived stress, 82% of variance in depressed mood, and 81% of variance in fatigue.
Depressed mood may partially explain the relationship between physical activity and perceived stress in middle-aged women, however further studies are needed to corroborate causality.
确定抑郁情绪和疲劳是否在身体活动、体重指数、绝经热潮红和感知压力之间的关系中起中介作用。
本研究是对妇女健康 TREMIN 研究计划中围绝经期和绝经后妇女（N=212）子样本数据的二次分析。
使用 Mplus 版本 5.1 中的结构方程建模框架内的路径分析检验了假设的中介模型。在未调整的分析中，身体活动、绝经热潮红和感知压力之间的关系受抑郁情绪影响；疲劳中介了热潮红、体重指数和感知压力之间的关系。当调整年龄、失眠、绝经和激素使用状况时，抑郁情绪对压力的中介作用仅在身体活动中仍然显著，而疲劳则介导了热潮红和压力之间的关系。调整后的模型解释了感知压力的 70%、抑郁情绪的 82%和疲劳的 81%的方差。
抑郁情绪可能部分解释了中年妇女身体活动与感知压力之间的关系，但需要进一步研究来证实因果关系。
