First Department of Internal Medicine, Nissay Hospital, 6-3-8 Itachibori Nishi-ku, Osaka City, Osaka, Japan.
J Cardiol. 2009 Oct;54(2):307-10. doi: 10.1016/j.jjcc.2008.12.010. Epub 2009 Feb 12.
This is a case of a thrombo-occlusion occurring below an inferior vena cava (IVC) filter inserted in a patient with polycythemia vera and deep vein thrombosis. The patient was a 48-year-old man with polycythemia vera and a chief complaint of swelling, redness, and bursting pain in his right leg. After admission, contrast-enhanced computed tomography scanning demonstrated a pulmonary artery thrombus and deep vein thrombosis. We inserted a Gunther tulip vena cava filter on day 1 for the prevention of pulmonary embolism (PE), and started anticoagulation therapy based on the guideline of the Japanese Circulation Society for DVT. In addition to intravenous anticoagulants, we started therapeutic phlebotomy to improve the hypercoagulability state. On day 4, our patient complained of back pain caused by thrombo-occlusion below the IVC filter, despite the anticoagulation therapy and two therapeutic phlebotomies. From this case, we concluded it is important to lower hemoglobin level and hematocrit as early as possible for IVC-filter-insertion in patients with polycythemia vera.
这是一例下腔静脉滤器置入后发生血栓阻塞的病例,患者患有真性红细胞增多症和深静脉血栓形成。患者为 48 岁男性,患有真性红细胞增多症,主诉右下肢肿胀、发红和剧痛。入院后,增强 CT 扫描显示肺动脉血栓和深静脉血栓形成。为预防肺栓塞(PE),我们在第 1 天置入了 Gunther tulip 下腔静脉滤器,并根据日本循环学会的 DVT 指南开始抗凝治疗。除了静脉内抗凝剂,我们还开始了治疗性放血以改善高凝状态。第 4 天,尽管进行了抗凝治疗和两次治疗性放血,但我们的患者仍出现了由 IVC 滤器下方血栓阻塞引起的背痛。从这个病例中,我们得出结论,对于真性红细胞增多症患者,尽早降低血红蛋白和血细胞比容水平对于下腔静脉滤器置入非常重要。