Dipartimento di Chimica Organica A. Mangini, Università di Bologna, I-40136 Bologna, Italy.
Bioorg Med Chem Lett. 2009 Nov 1;19(21):6092-4. doi: 10.1016/j.bmcl.2009.09.030. Epub 2009 Sep 12.
Hydrogen sulfide has recently been considered to have an important role as a gasotransmitter in the cardiovascular system as well as in the central nervous system, but its action seems directly related to the presence of nitric oxide/nitric oxide-derivatives. We report here chemical evidence that emphasizes a prominent role of the hydrogen sulfide as cofactor of NO-derivatives in inducing nitric oxide release.
硫化氢最近被认为在心血管系统和中枢神经系统中作为一种气体递质具有重要作用，但它的作用似乎与一氧化氮/一氧化氮衍生物的存在直接相关。我们在这里报告了化学证据，强调了硫化氢作为一氧化氮衍生物诱导一氧化氮释放的辅助因子的突出作用。
