Zalaudek Iris, Manzo Manuela, Savarese Imma, Docimo Giovanni, Ferrara Gerardo, Argenziano Giuseppe
Division of Dermatology, Medical University of Graz, Graz, Austria.
Semin Cutan Med Surg. 2009 Sep;28(3):149-56. doi: 10.1016/j.sder.2009.06.005.
Different types of nevi do exist in relation to their epidemiology, morphology, evolution, and associated melanoma risk. The introduction of dermoscopy opened a new dimension of the morphologic universe of nevi and allowed clinicians to observe colors and structures within nevi that are otherwise not visible to the unaided eye. Because most of these colors and structures correspond to well-defined histopathologic correlates, dermoscopy enables clinicians to date to more precisely predict the histopathology diagnosis and thereby improve on their clinical diagnostic accuracy. Besides the diagnostic impact, the in vivo observation of thousands of nevi using dermoscopy and digital dermoscopic follow-up has opened new understanding about the evolution of nevi and factors influencing the nevus pattern. In consequence, a new nevus classification has been proposed, subdividing nevi into 7 categories, which are as follows: (1) globular/cobblestone nevi, (2) reticular nevi, (3) starburst nevi, (4) homogeneous blue nevi, (5) nevi on special body sites, (6) nevi with special features, and (7) and unclassifiable melanocytic proliferations. This article provides an overview on the morphologic classification of nevi and the factors influencing the nevus pattern.
根据流行病学、形态学、演变过程及相关黑色素瘤风险的不同，的确存在不同类型的痣。皮肤镜的引入为痣的形态学领域开启了一个新维度，使临床医生能够观察到痣内部那些肉眼无法看到的颜色和结构。由于这些颜色和结构大多与明确的组织病理学特征相对应，皮肤镜使临床医生能够更精确地预测组织病理学诊断结果，从而提高临床诊断准确性。除了诊断方面的影响，利用皮肤镜对数千颗痣进行活体观察以及数字皮肤镜随访，开启了对痣的演变过程和影响痣形态的因素的新认识。因此，有人提出了一种新的痣分类方法，将痣分为7类，具体如下：（1）球状/鹅卵石样痣；（2）网状痣；（3）星芒状痣；（4）均匀蓝色痣；（5）特殊身体部位的痣；（6）具有特殊特征的痣；（7）无法分类的黑素细胞增殖。本文概述了痣的形态学分类以及影响痣形态的因素。
