Department of Obstetrics and Gynecology, San Juan University Hospital, Alicante, Spain.
Int J Gynaecol Obstet. 2010 Jan;108(1):16-20. doi: 10.1016/j.ijgo.2009.08.019.
To analyze the clinical, therapeutic, and pathologic features of published cases presenting primary squamous cell carcinoma (SCC) of the ovary associated with endometriosis.
A case report, 15 cases of infiltrating SCC of the ovary associated with or arising from endometriosis, and 1 case of synchronous carcinoma in situ in the cervix and ovary from a review of the literature were studied.
Young age, advanced stage of the disease, and hypogastric pain were frequent at the time of diagnosis. There was no ascites, but infiltration of neighboring organs was common. The tumor was associated with 80% patient mortality in the first few months. Adjuvant chemotherapy with paclitaxel and carboplatin or cisplatin appeared to improve the results.
Primary SCC of the ovary associated with endometriosis is extremely rare and has a poor prognosis. The best therapeutic results are obtained with paclitaxel and carboplatin or cisplatin after radical surgery.
分析已发表的原发性卵巢鳞状细胞癌（SCC）合并子宫内膜异位症病例的临床、治疗和病理特征。
对 1 例病例报告、15 例浸润性卵巢 SCC 合并或源自子宫内膜异位症，以及 1 例同时发生在宫颈和卵巢的原位癌进行了文献复习。
诊断时，患者年龄较小，疾病处于晚期，且常有下腹疼痛。无腹水，但常见邻近器官浸润。肿瘤在最初几个月导致 80%的患者死亡。紫杉醇和卡铂或顺铂辅助化疗似乎改善了结果。
原发性卵巢 SCC 合并子宫内膜异位症极为罕见，预后不良。在根治性手术后，紫杉醇和卡铂或顺铂联合治疗可获得最佳疗效。
