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Forensic Sci Int. 2009 Jul 1;188(1-3):144-51. doi: 10.1016/j.forsciint.2009.04.005. Epub 2009 Apr 29.
2
Validation of analysis of amphetamines, opiates, phencyclidine, cocaine, and benzoylecgonine in oral fluids by liquid chromatography-tandem mass spectrometry.液相色谱-串联质谱法对口腔液中苯丙胺、阿片类药物、苯环利定、可卡因和苯甲酰爱康宁分析的验证
J Anal Toxicol. 2008 Oct;32(8):605-11. doi: 10.1093/jat/32.8.605.
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Drug screening of hair by liquid chromatography-tandem mass spectrometry.通过液相色谱-串联质谱法对毛发进行药物筛查。
J Anal Toxicol. 2008 Jun;32(5):364-72. doi: 10.1093/jat/32.5.364.
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Development and validation of a liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry method for simultaneous analysis of 10 amphetamine-, methamphetamine- and 3,4-methylenedioxymethamphetamine-related (MDMA) analytes in human meconium.一种用于同时分析人胎粪中10种与苯丙胺、甲基苯丙胺和3,4-亚甲基二氧甲基苯丙胺（摇头丸）相关分析物的液相色谱-大气压化学电离-串联质谱法的开发与验证
J Chromatogr B Analyt Technol Biomed Life Sci. 2008 May 15;867(2):194-204. doi: 10.1016/j.jchromb.2008.03.029. Epub 2008 Apr 4.
5
Bioanalytical procedures for monitoring in utero drug exposure.监测子宫内药物暴露的生物分析程序。
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Intrapartum and postdelivery management of infants born to mothers with meconium-stained amniotic fluid: evidence-based recommendations.羊水胎粪污染母亲所分娩婴儿的产时及产后管理：循证推荐意见
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Clin Chim Acta. 2006 Apr;366(1-2):101-11. doi: 10.1016/j.cca.2005.10.028. Epub 2006 Jan 17.
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The characterisation of selected drugs with amine-containing side chains using electrospray ionisation and ion trap mass spectrometry and their determination by HPLC-ESI-MS.使用电喷雾电离和离子阱质谱对选定的含胺侧链药物进行表征，并通过高效液相色谱-电喷雾电离-质谱对其进行测定。
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Anal Chem. 2003 Jul 1;75(13):3019-30. doi: 10.1021/ac020361s.

采用液相色谱-串联质谱法测定脐带中苯丙胺和甲基苯丙胺。

Determination of amphetamine and methamphetamine in umbilical cord using liquid chromatography-tandem mass spectrometry.

作者信息

Jones Joseph, Rios Rosemarie, Jones Mary, Lewis Douglas, Plate Charles

机构信息

United States Drug Testing Laboratories, Des Plaines, IL 60018, United States.

出版信息

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Nov 1;877(29):3701-6. doi: 10.1016/j.jchromb.2009.09.021. Epub 2009 Sep 19.

DOI:10.1016/j.jchromb.2009.09.021
PMID:19783234
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2782418/
Abstract

The use of meconium as a drug-screening matrix for newborns has been the gold standard of care for the past two decades. A recent study using matched pairs of meconium and umbilical cord demonstrated a high degree of agreement. The use of liquid chromatography-tandem mass spectrometry as a means to confirm amphetamines presumptive positive umbilical cord specimens for amphetamine and methamphetamine is described here for the first time. The limit of detection for both compounds was 0.2 ng/g. The limit of quantitation for both compounds was 0.6 ng/g. The assay was linear for both compounds up to 100 ng/g.

摘要

在过去二十年里，使用胎粪作为新生儿药物筛查基质一直是护理的金标准。最近一项使用配对胎粪和脐带样本的研究显示出高度一致性。本文首次描述了使用液相色谱 - 串联质谱法来确认脐带样本中苯丙胺和甲基苯丙胺疑似阳性的情况。两种化合物的检测限均为0.2 ng/g。两种化合物的定量限均为0.6 ng/g。该检测方法对两种化合物在高达100 ng/g的范围内呈线性。