Cinteză M, Cerin G, Bogdan M, Dorobanţu M, Dimulescu D, Dăian C, Iosifescu D, Potcovaru D, Gherasim I
Clinica Medicală III, Spitalul Clinic Municipal, Bucureşti.
Rev Med Interna Neurol Psihiatr Neurochir Dermatovenerol Med Interna. 1990 Jan-Feb;42(1):35-47.
The incidence, etiology and data on the severity and therapeutic implications of the mitral insufficiency were investigated in the patients admitted in the clinic during 10 years. The diagnosis was based mainly on clinical and echocardiography mode M data. 595 patients suffering from mitral insufficiency (below 2% of the total of the patients admitted) were recorded. In 65% of the cases mitral insufficiency had a rheumatic etiology (the majority associated polyvalvulopathies), in 14.8% an ischaemic origin, and in 10.9% an organic-functional one (the left ventricle was dilated). The primary prolapse of the mitral valve appeared in 6.9% of the cases (the low incidence was explained by the severe criteria applied in positive diagnosis). 4 cases of rupture of the subvalvular apparatus are described in the patients suffering from prolapse. All of them had a sudden onset, by severe cardiac insufficiency without a clear cause, appeared under conditions of seemingly complete health. Intense therapy followed by valvular prosthesis, resulted in a spectacular recovery of the heart function.
对10年间该诊所收治的患者中二尖瓣关闭不全的发病率、病因以及严重程度和治疗意义的数据进行了调查。诊断主要基于临床和超声心动图M型数据。记录了595例二尖瓣关闭不全患者(占收治患者总数的2%以下)。65%的病例中二尖瓣关闭不全有风湿性病因(大多数伴有多瓣膜病变),14.8%为缺血性病因,10.9%为器质性功能性病因(左心室扩张)。二尖瓣原发性脱垂出现在6.9%的病例中(低发病率是由于阳性诊断采用了严格标准)。在脱垂患者中描述了4例瓣下装置破裂。所有病例均突然起病,表现为严重的心功能不全且无明确病因,出现在看似完全健康的情况下。经过强化治疗后进行瓣膜置换,心功能得到了显著恢复。